Sigma-Aldrich
Fluka & Supelco - Analytical Logo
Decrease Font Size Increase Font Size Email this page to a friend Printer Friendly Page
Residue Analysis

Vetranal Standards

Nitrofuran Antibiotics
Detailed Product List

Nitrofuran Antibiotics

During an investigation early in 2002, it was discovered that residues of nitrofuran antibiotics occurred in fish products like shrimp and catfish originating from South-East Asian countries. Later on, intensified control revealed that the same residues could also be found in poultry, duck and rabbit imported from this region.

Since the discovery of the occurrence of residues of nitrofurans and their metabolites (AOZ (3-Amino-2-oxazolidinone), AMOZ (5-Methylmorpholino-3-amino-2-oxazolidinone), AHD (1-Aminohydantoin hydrochloride) and SEM (Semicarbazide hydrochloride), numerous scientists have contacted Sigma-Aldrich and asked for analytical standards. In 2003, we launched following 4 standards:


Abbreviation
Name
Catalog No.
AOZ
(3-Amino-2-oxazolidinone)
AMOZ
(5-Methylmorpholino-3-amino-2-oxazolidinone):
AHD
(1-Aminohydantoin hydrochloride)
SEM
(Semicarbazide hydrochloride)

Afterwards, many customers asked if we can provide also the derivatized and isotope- labelled standards. In order to provide the best and most convenient analytical solution we have developed 7 more Nitrofuran Standardswhich will allow you to reduce the analysis time significantly:

Nitrofuran standards derivatized with 2-nitrobenzaldehyde which are most common standards used in nitrofuran analysis.


Abbreviation
Name
Catalog No.
2-NP-AOZ
(3-(2-Nitrobenzylidenamino)-2-oxazolidinone)
2-NP-SCA
(2-Nitrobenzaldehyde semicarbazone)
2-NP-AMOZ
(5-(Morpholinomethyl)-3-(2-nitrobenzylidenamino)-2-oxazolidinone)
2-NP-AHD
(3-(2-Nitrobenzylidenamino)-2,4-imidazolidinedione)
For scientists performing nitrofuran analysis by LC-MS we are pleased to provide 3 unique isotope marked standards:


Abbreviation
Pack-size
Catalog No.
AOZ-D4
10mg
AMOZ-D5
10mg
SCA-HCL (13C, 15N)
10mg



References:
"Determination of the metabolites of nitrofuran antibiotics in animals tissues by HPLC-tandem mass spectrometry", A. Leitner, P. Zvllner, W. Lindner, J. Chromatogr. A, 939 (2001) 49-58.

"Analysis of protein-bound metabolites of furazolidone and furaltadone in pig liver by high performance liquid chromatography and liquid chromatography-mass spectrometry.", E. Horne, A. Cadogan, M. O'Keeffe and L.A.P. Hoogenboom, The Analyst, 121 (1996) 1463-1468.

"The use of pig hepatocytes to study the nature of protein-bound metabolites of furazolidone; a new analytical method for their detection.", L.A.P. Hoogenboom, M. van Kammen, M.C.J. Berghmans, J.H. Koeman and H.A. Kuiper, Food and Chemical Toxicology, 29 (1991) 321-328.

Back to Top





Detailed Product List


Prod. No.
Name
Application
Pack Size
46060
Amoxicillin, trihydrate antibiotic 250 mg
46006
Amphotericin B, trihydrate antibiotic 100 mg
46061
Ampicillin, trihydrate antibiotic 250 mg
46062
Amprolium hydrochloride   250 mg
46024
Androstanolone hormone 250 mg
46025
Androstanolone 17-benzoate hormone 250 mg
46033
Androstenedione hormone 250 mg
46041
Androsterone hormone 250 mg
46042
Androsterone 3-acetate hormone 100 mg
46063
Arecoline hydrobromide   250 mg
46059
4-Arsanilic acid   250 mg
46084
Bacitracin A antibiotic 250 mg
46610
Benzathine penicillin G, tetrahydrate antibiotic 250 mg
46074
Betamethasone 17-valerate hormone 250 mg
46083
Bithionol   250 mg
46090
Boldenone hormone 250 mg
46091
Boldenone 17-acetate hormone 100 mg
46100
Carbazole phenothiazine 250 mg
46110
Chloramphenicol antibiotic 250 mg
46109
Chloramphenicol palmitate antibiotic 250 mg
46116
Chlormadinone 17-acetate hormone 100 mg
46125
Chlorpromazine hydrochloride phenothiazine 250 mg
46133
Chlortetracycline hydrochloride antibiotic 250 mg
46140
Cloxacillin sodium salt, hydrate antibiotic 250 mg
46148
Corticosterone hormone 100 mg
46149
Corticosterone 21-acetate hormone 100 mg
46364
Crystal violet chloride   250 mg
46158
Dapsone   250 mg
46161
Demeclocycline hydrochloride, hemihydrate antibiotic 100 mg
46165
Dexamethasone hormone 250 mg
46166
Dexamethasone 21-acetate hormone 250 mg
46174
Diaveridine diaminopyridine 100 mg
46182
Dicloxacillin sodium salt, hydrate antibiotic 100 mg
46190
Dienestrol hormone 250 mg
46191
Dienestrol diacetate hormone 250 mg
46200
Diethylcarbamazine citrate   250 mg
46207
Diethylstilbestrol hormone 250 mg
46224
Dimetridazole imidazole 250 mg
46232
Dipyrone, hydrate   250 mg
46239
Equilenin hormone 100 mg
33693
Equilenin Solution hormone 2 ml
46247
Equilin hormone 100 mg
46256
Erythromycin A, dihydrate antibiotic 250 mg
46551
17b-Estradiol 17-acetate hormone 100 mg
46552
17b-Estradiol 3-benzoate hormone 250 mg
46553
17b-Estradiol 3,17-diacetate hormone 100 mg
46554
17b-Estradiol 3,17-dipropionate hormone 250 mg
46542
17a-Estradiol, hemihydrate hormone 100 mg
46550
17b-Estradiol, hemihydrate hormone 250 mg
46555
17b-Estradiol 3-methyl ether hormone 250 mg
46556
17b-Estradiol 17-propionate hormone 250 mg
46557
17b-Estradiol 17-valerate hormone 250 mg
46565
Estriol hormone 100 mg
46573
Estrone hormone 250 mg
46263
17a-Ethinylestradiol hormone 250 mg
46272
Ethisterone hormone 250 mg
46280
Etiocholanolone hormone 100 mg
35032
Fenbendazole   100 mg
46289
Furaltadone   250 mg
46297
Furazolidone   250 mg
46305
Gentamycin 2,5-sulfate, hexahydrate antibiotic 250 mg
46309
Griseofulvin   250 mg
46313
Hexachloroethane   250 mg
46320
Hexestrol hormone 250 mg
46328
Hydrocortisone hormone 250 mg
46329
Hydrocortisone 21-acetate hormone 250 mg
46337
17a-Hydroxyprogesterone hormone 250 mg
46346
21-Hydroxyprogesterone hormone 250 mg
46338
17a-Hydroxyprogesterone 17-acetate hormone 250 mg
46347
21-Hydroxyprogesterone 21-acetate hormone 250 mg
46356
Kanamycin A disulfate, dihydrate antibiotic 250 mg
46372
Lasalocid A sodium salt   250 mg
46380
Leucomycin, hydrate antibiotic 250 mg
46944
Levamisole hydrochloride imidazole 250 mg
46387
Lincomycin hydrochloride, hydrate antibiotic 250 mg
46396
Malachite green oxalate   250 mg
46404
Mebendazol   250 mg
46411
Medroxyprogesterone hormone 100 mg
46412
Medroxyprogesterone 17-acetate hormone 250 mg
46420
Megestrol 17-acetate hormone 100 mg
46264
Mestranol hormone 250 mg
46429
Methimazole   250 mg
46436
6a-Methylprednisolone hormone 100 mg
46444
17a-Methyltestosterone hormone 250 mg
46453
6-Methyl-2-thiouracil thiouracil 250 mg
46461
Metronidazole imidazole 250 mg
46468
Monensin sodium salt, hydrate antibiotic 100 mg
46473
Morantel tartrate   250 mg
46476
Nandrolone hormone 250 mg
46477
Nandrolone 17-propionate hormone 100 mg
46482
Naproxen   250 mg
46486
Neomycin B trisulfate sesquihydrate   250 mg
46494
Nifuroxazide nitrofurane 250 mg
46502
Nitrofurantoin nitrofurane 250 mg
46208
Nitrofurazon solution, 100 ng/ml, in acetonitrile   2 ml, 10 ml
46518
Nitromide   250 mg
46525
19-Norethisterone hormone 250 mg
46527
19-Norethisterone 17-acetate   100 mg
46531
Novobiocin sodium salt   250 mg
46535
Nystatin A1, trihydrate antibiotic 250 mg
46582
Oleandomycin phosphate, dihydrate antibiotic 250 mg
46589
Oxacillin sodium salt, hydrate antibiotic 100 mg
46598
Oxytetracycline hydrochloride antibiotic 250 mg
46609
Penicillin G potassium salt antibiotic 250 mg
46616
Penicillin V potassium salt antibiotic 250 mg
46624
Phenothiazine   250 mg
46901
N4-Phthalylsulfathiazole sulfonamide 250 mg
46632
Piperazine citrate, pentahydrate   250 mg
46639
Polymyxin B 2,5-sulfate, pentahydrate antibiotic 100 mg
46648
Praziquantel   250 mg
46656
Prednisolone hormone 250 mg
46657
Prednisolone 21-acetate hormone 250 mg
46608
Procaine hydrochloride   250 mg
46665
Progesterone hormone 250 mg
46674
Promazine hydrochloride   250 mg
46682
Promethazine hydrochloride   250 mg
46689
Propionylpromazine hydrochloride   100 mg
46698
6-Propyl-2-thiouracil   250 mg
46702
Pyrantel pamoate   250 mg
46706
Pyrimethamine   250 mg
46713
Rifamycin AMP antibiotic 100 mg
46721
Rifamycin SV sodium salt, hexahydrate antibiotic 100 mg
46724
Roxarsone   250 mg
46725
Salbutamol   100 mg
46732
Salbutamol hemisulfate   250 mg
46729
Salinomycin SV sodium salt, 2,5-hydrate antibiotic 100 mg
46738
Spectinomycin dihydrochloride, pentahydrate antibiotic 250 mg
46745
Spiramycin (I) antibiotic 100 mg
46754
Streptomycin sesquisulfate antibiotic 250 mg
46900
N4-Succinylsulfathiazole, monohydrate sulfonamide 250 mg
46762
Sulfabenzamide   250 mg
46770
Sulfacetamide   250 mg
46778
Sulfachlorpyridazine sulfonamide 250 mg
35033
Sulfadiazine   100 mg
46794
Sulfadimethoxine sulfonamide 250 mg
46802
Sulfadimidine sulfonamide 250 mg
46810
Sulfadoxine   250 mg
46818
Sulfaguanidine, monohydrate sulfonamide 250 mg
46826
Sulfamerazine sulfonamide 250 mg
46834
Sulfameter sulfonamide 250 mg
46842
Sulfamethizole sulfonamide 250 mg
46850
Sulfamethoxazole sulfonamide 250 mg
46858
Sulfamethoxypyridazine sulfonamide 250 mg
46866
Sulfamoxole sulfonamide 250 mg
46874
Sulfanilamide sulfonamide 250 mg
46882
Sulfanitran sulfonamide 250 mg
46890
Sulfapyridine sulfonamide 250 mg
46902
Sulfathiazole sulfonamide 250 mg
46908
Sulfisomidine sulfonamide 250 mg
46916
Sulfisoxazole sulfonamide 250 mg
46923
Testosterone hormone 250 mg
46924
Testosterone 17-acetate hormone 250 mg
46926
Testosterone 17-benzoate