|
Standards are necessary to standardize and control reagents, check the reliability of titrations and test instruments according to the requirements of ISO 9000, GMP, GLP and FDA guidelines.
ISO 9001 requires: "The supplier shall control, calibrate ... measuring and test equipment ...
to demonstrate the conformance". Karl Fischer titrators are such instruments and must be controlled on a regular basis.
It is part of a quality assurance system.
The HYDRANAL®-Water Standards are standards for volumetric or coulometric determinations. They are delivered with a "Certificate of Analysis"
giving the actual water content. The liquid standards are packaged in glass ampoules under argon. A box contains 10 ampoules.
Each ampoule is designed for one use. The shelf life is more than 5 years.
Advantages of HYDRANAL®-Water Standards
- Packaged in glass ampoules under argon.
- Each ampoule only for one use.
- Shelf life 5 years.
- Contains instruction for use according to guide lines like ISO 9001.
- Manufactured by a company certified ISO 9001.
- Certificate of Analysis enclosed in each pack.
- Tested against NIST SRM 2890.
View Product List and Ordering Information
New 37943 Fastrate™ 10 mg volumetric
10.00 ± 0.3 mg water/tablet
Solid Dose Calibration Standard for volumetric Karl Fischer titration
We are exclusively distributing Fastrate™ 10 mg volumetric*, a novel water standard in tablet form to support volumetric Karl Fischer titrations. The tablets are manufactured and packaged in single use, individually sealed foil pouches and are supplied with a Certificate of Analysis (CoA) delivered with each carton. A 10 mg water content meets the minimum water content required by pharmacopoeia standards (e.g. USP General Chapter 921. Water Determination). Fastrate™ 10 mg volumetric is available in a pack of 30 tablets.
Usage
The Fastrate™ 10mg volumetric tablets simplify your instrument calibration. Open a pouch and put the water standard tablet into your volumetric titration vessel. The deviation from the water content described in the CoA does not exceed 3% (w/w). If you require a more accurate content, we recommend to use HYDRANAL® Water Standards.
*Licensed from Facet Analytical Services and Technology, LLC
U.S. Patents 7,049,146 and 7,122,376 and foreign equivalents apply
New 34694 HYDRANAL®-Water Standard Oil
Measuring the water content of oily samples can be a challenge. Their inherently low water content and compatibility of the titration technique, reagents and instruments with this type of sample are complicating factors. Additionally, for accurate determinations, the water content standards should have similar composition to the sample.
To help analysts maximize the accuracy and the ease of water determination of oily samples by Karl Fischer titration, we have developed mineral oil-based HYDRANAL®- Water Standard Oil. The water content of each lot is analysed using several procedures applied in practice: direct volumetric and coulometric Karl Fischer titration as well as the indirect procedure using a Karl Fischer oven (Figure 1). Actual water content of the standard is reported on the Certificate of Analysis included with each box. HYDRANAL®- Water Standard Oil is tested against NIST SRM 2890.
Figure 1 … Temperature ramp HYDRANAL®- Water Standard Oil
Literature
Back to top
Back to HYDRANAL®-home
|
