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Access the matrix metalloproteinase you are interested by the links below:
Complete list of Matrix Metalloproteinase products
Feature Article: "Matrix Metalloproteinases and their Inhibitors - Current Status and Future Challenges"
| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-1 |
Collagenase (Type I, interstitial) |
3.4.24.7 |
Collagens (I, II, III, VII, VIII, and X); gelatin; aggrecan; L-selectin; IL-1beta; proteoglycans; entactin; ovostatin; MMP-2; MMP-9 |
| MMP-3 |
Stromelysin-1, Proteoglycanase |
3.4.24.17 |
Collagens (III, IV, V, and IX); gelatin; aggrecan; perlecan; decorin; laminin; elastin; caesin; osteonectin; ovostatin; entactin; plasminogen; MBP; IL-1beta; MMP-2/TIMP-2; MMP-7; MMP-8; MMP-9; MMP-13 |
| MMP-8 |
Neutrophil collagenase |
3.4.24.34 |
Collagens (I, II, III, V, VII, VIII, and X); gelatin; aggrecan; fibronectin |
| MMP-10 |
Stromelysin-2 |
3.4.24.22 |
Collagens (III-V); gelatin; casein; aggrecan; elastin; MMP-1; MMP-8 |
| MMP-12 |
Macrophage metalloelastase |
3.4.24.65 |
Collagen IV; gelatin; elastin; casein; fibronectin; vitronectin; laminin; entactin; MBP; fibrinogen; fibrin; plasminogen |
| MMP-13 |
Collagenase-3 |
* |
Collagens (I, II, III, IV, IX, X, and XIV); gelatin; plasminogen;aggrecan; perlecan; fibronectin; osteonectin; MMP-9 |
| MMP-18 |
Xenopus Collagenase-4 |
* |
Type I collagen |
| MMP-19 |
RASI |
* |
Type I collagen |
| MMP-20 |
Enamelysin |
3.4.24 |
Amelogenin; aggrecan, and cartilage oligomeric matrix protein (COMP) |
| MMP-22 |
Chicken MMP (C-MMP) |
* |
Unknown |
| MMP-27 |
|
* |
Unknown |
| MMP-28 |
Epilysin |
* |
Unknown |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-2 |
Gelatinase A 72 kDa Gelatinase Type IV Collagenase |
3.4.24.24 |
|
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-7 |
Matrilysin; PUMP |
3.4.24.23 |
Collagens (IV and X); gelatin; aggrecan; decorin; fibronectin; laminin; entactin; elastin; casein; transferrin; plasminogen; MBP; Beta4-intergrin; MMP-1; MMP-2; MMP-9; MMP-9/TIMP-1 |
| MMP-26 |
Matrilysin-2; Endometase |
* |
Collagen IV, fibronectin, fibrinogen, gelatin, alpha (1)-proteinase inhibitor |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-9 |
Gelatinase B |
3.4.24.35 |
Collagens (IV, V, VII, X, and XIV); gelatin; entactin; aggrecan; elastin; fibronectin; osteonectin; plasminogen; MBP; IL-1beta |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-11 |
Stromelysin-3 |
3.4.24 |
Unknown (casein) |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-14 |
MT1-MMP |
3.4.24 |
Collagens (I-III); gelatin; casein; fibronectin; laminin; vitronectin; entactin; proteoglycans; MMP-2; MMP-13 |
| MMP-15 |
MT2-MMP |
3.4.24 |
Fibronectin; entactin; laminin; aggrecan; perlecan; MMP-2 |
| MMP-16 |
MT3-MMP |
3.4.24 |
Collagen III; gelatin; casein; fibronectin; MMP-2 |
| MMP-24 |
MT5-MMP |
* |
Fibronectin, but not collagen type I nor laminin |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-17 |
MT4-MMP |
3.4.24 |
Unknown |
| MMP-25 |
MT6-MMP; leukolysin |
* |
Pro-gelatinase A |
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| MMP |
Alternative Name |
EC Number |
Substrates |
| MMP-21 |
Xenopus MMP (X-MMP) |
* |
Unknown |
| MMP-23 |
Cysteine Array Matrix Metalloproteinase (CA-MMP) |
* |
Unknown |
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* EC Number not assigned.
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