Proteasome, Calpain and Lysosomal Proteases

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Ubiquitination
	Enzyme Explorer

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Overview of Ubiquitin and the Proteasome Pathway

Product Guide:

Proteasome Pathway
Proteasomes
Calpain
Lysosomal Proteases

Proteasome Pathway
Ubiquitination
Enzymes/Proteins
Prod No.:	Product Name:
I 1154	Isopeptidase T	*New
U 1633	Ubiquitin Activating Enzyme, Yeast	*New
U 1758	Ubiquitin Activating Enzyme, Rabbit	*New
U 2133	Ubiquitin C-Terminal Hydrolase, L3	*New
U 8382	Ubiquitin conjugating enzyme fractions (mammalian)	*New
U 2633	Ubiquitin Carrier Protein H2 / E2-14K	*New
U 2508	Ubiquitin Carrier Protein H2	*New
U 2383	Ubiquitin Carrier Protein H3	*New
U 8632	Ubiquitin-Carrier Protein H5a, GST-tagged human	*New
U 8757	Ubiquitin-Carrier Protein H5b human	*New
U 8882	Ubiquitin-Carrier Protein H5c human	*New
U 9007	Ubiquitin-Carrier Protein H6 human	*New
U 9132	Ubiquitin-Carrier Protein H7 human	*New
U 9257	Ubiquitin-Carrier Protein H9 human	*New
U 9382	Ubiquitin-Carrier Protein H10 human	*New
U 5382	Ubiquitin, human, recombinant, N-terminal FLAG-tagged
U 5507	Ubiquitin, human, recombinant, N-terminal his-tagged
U 5632	Ubiquitin-Agarose
U 6253	Ubiquitin from bovine erythrocytes
U 8257	Ubiquitin Fraction FI from HeLa cells	*New
U 8507	Ubiquitin K48R	*New
Inhibitors
U 1507	Ubiquitin Aldehyde
U 1632	Ubiquitin, Methylated
Substrates
N 2030	NEDD8 precursor (Pro NEDD8)	*New
N 8529	NEDD8	*New
S 0314	SUMO-1/Sentrin-1 human	*New
S 0439	SUMO-1/Sentrin-1 human	*New
U 5379	Anti-Ubiquitin from rabbit
U 2258	Ubiquitin-AMC	*New
Proteasomes
Proteasome Fractions
F 3926	Fraction II [FII] (HELA)	*New
F 4051	Fraction II [FII] (Rabbit reticulocyte)	*New
P 3863	26S Proteasome Fraction from rabbit	*New
P 3988	20S proteasome (mammalian)	*New
P 4113	S-100 proteasome fraction from HeLa cells	*New
Inhibitors
C 0358	CBZ-Leu-Leu-Phe-Al	*New
C 2211	N-CBZ-Leu-Leu-Leucinal
C 6706	N-CBZ-Leu-Leu-Norvalinal
C 9857	CBZ-Leu-Leu-Leu-B(OH)2	*New
E 3652	Epoxomicin	*New
E 3876	N-Ethylmaleimide
L 7035	clasto-Lactacystin b-lactone
L 6785	Lactacystin
G 9893	Gliotoxin
Substrates
C 0483	Z-Leu-Leu-Glu-7-amido-4-methylcoumarin	*New
C 0608	Z-Leu-Leu-Leu-7-amido-4-methylcoumarin	*New
C 0788	CBZ-Leu-Leu-Glu-ß-naphthylamide	*New
Activator
P 5988	PA28 activator (mammalian)	*New
Calpain
Enzymes
C 6108	Calpain I	*New
P 4533	Calpain II
Inhibitors
A 6060	N-acetyl-Leu-Leu-Methioninal
A 6185	Calpain Inhibitor I
A 6191	Antipain Hydrochloride
C 4285	Acetyl-Calpastatin (184-210) Human
C 5913	4-Chloromercuribenzoic acid
C 8984	Z-Leu-Leu-Leu-fluoromethyl keytone	*New
C 9181	Calpain Inhibitor Peptide
C 9234	Z-Leu-Leu-Tyr-fluoromethyl ketone	*New
C 9859	Z-Leu-Leu-Tyr-CHN₂	*New
E 0514	E-64c
E 8640	E-64d
L 2023	Leupeptin Trifluoroacetate salt
M 5439	N-Methoxysuccinyl-Val-HOMO-Phe-fluoromethyl ketone	*New
M 6159	a₂-Macroglobulin
M 6690	MDL 28170 (Calpain III inhibitor)	*New
Substrates
S 1153	N-Succinyl-Leu-Tyr 7-amido-4-methylcoumarin
S 6510	Succinyl-Leu-Leu-Val-Tyr 7-amido-4-methylcoumarin
Antibodies
C 0230	Monoclonal Anti-m/5 Calpain, Small Subunit from mouse	*New
C 0355	Monoclonal Anti-mu Calpain, Large Subunit, Clone 15C10, Mouse	*New
C-269	Anti-Calpain (28 kDa subunit), monoclonal
C 5361	Anti-Mu-Calpain (Domain I) N-terminal
C 5486	Anti-Mu-Calpain (Domain I)
C 5861	Anti-Mu-Calpain (Domain I) N-terminal
C-266	Anti-mu-Calpain (Domain II), monoclonal
C-267	Anti-mu-Calpain (Domain II), monoclonal
C 0728	Anti-mu-Calpain Domain-III, large subunit
C-268	Anti-mu-Calpain (Domain III/IV), monoclonal
C 6111	Anti-M-Calpain (Domain III)
C 0478	Anti-LP-85 (lens-specific Calpain); Domain-IV, large subunit
C 0603	Anti-LP-82 (lens-specific Calpain)and LP-85; Domain-III, large subunit
C 6611	Anti-Calpain-94 (Domain I)
C 6486	Anti-Calpain-94 (Domain III)
C 6361	Anti-Calpain-94 (Domain II-Insert 1)
C 6236	Anti-Calpain-94 (Domain III-Insert 2)
C 5611	Anti-Mu-Calpain (Domain IV)
C 5736	Anti-Mu-Calpain (Domain IV) C-terminal
C 5986	Anti-Mu-Calpain (Domain IV) C-terminal
C-270	Anti-Calpastatin, monoclonal
Lysosomal Proteases
Cathepsin B
Enzymes
C 6286	Cathepsin B from bovine spleen
C 8571	Cathepsin B from human liver
C 0150	Cathepsin B from human placenta
Inhibitors
A 6060	N-Acetyl-Leu-Leu-Met-al
A 6185	N-Acetyl-Leu-Leu-Norleu-al
A 6191	Antipain Hydrochloride
B 1932	Biotin-Phe-Ala-fluoromethyl ketone	*New
C 0408	Cystatin
C 5732	CA-074	*New
C 5857	CA-074 Methyl Ester	*New
C 7268	Chymostatin
C 8917	Cystatin
C 9109	Z-Phe-Phe-fluoromethyl keytone	*New
E 3132	E-64
L 2023	Leupeptin Trifluoroacetate Salt
M 5314	N-Methoxysuccinyl-Phe-HOMO-Phe-fluoromethyl ketone	*New
M 6159	a₂-Macroglobulin
P 0350	Procathepsin B Fragment 26-50, rat
P 0475	Procathepsin B Fragment 36-50, rat
Substrates
B 0885	Na-Benzoyl-L-arginine 4-methoxy-ß-naphthylamide HCl
C 2772	Z-Val-Lys-Lys-Arg-4-methoxy-b-naphthylamide trihydrochloride
C 3282	Z-Phe-Arg 4-methoxy-b-naphthylamide hydrochloride
C 5429	Z-Arg-Arg-7-amido-4-Z-RR-AMC-methylcoumarin hydrochloride
C 5520	Z-Arg-Arg 4-methoxy-b-naphthylamide acetate salt
C 8536	Z-Ala-Arg-Arg 4-methoxy-b-naphthylamide acetate salt
H 2508	Hippuryl-Arg
S 6510	N-Succinyl-Leu-Leu-Val-Tyr-7-Amido-4-Methylcoumarin
Cathepsin D
Enzymes
C 3138	Cathepsin D, Bovine
C 8696	Cathepsin D, Human
Inhibitors
A 6191	Antipain Hydrochloride
C 7268	Chymostatin
P 5318	Pepstatin A
Substrates
C 6358	N-Acetyl-Arg-Gly-Phe-Phe-Pro-7-amido-4-methylcoumarin	*New
C 6983	N-Acetyl-Arg-Gly-Phe-Phe-Pro-7-amido-4-trifluoromethylcoumarin	*New
M 0938	7-Methoxycoumarin-4-Acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys (DNP)-D-Arg-amide	*New
Antibodies
C 0715	Anti-Cathepsin D
Cathepsin H
Enzymes
C 8821	Cathepsin H, Human Liver	*New
Inhibitors
C 0408	Cystatin
K 1632	Kininogen
L 2023	Leupeptin Trifluoroacetate Salt
Substrates
A 2027	L-Arginine-7-amido-4-methylcoumarin hydrochloride
Cathepsin L
Enzymes
C 6854	Cathepsin L, Human Liver	*New
Inhibitors
A 6185	N-Acetyl-Leu-Leu-Norleu-al
C 9109	Z-Phe-Phe-fluoromethyl keytone	*New
C 9234	Z-Leu-Leu-Tyr-fluoromethyl ketone	*New
C 9859	Z-Leu-Leu-Tyr-CHN₂	*New
M 5314	N-Methoxysuccinyl-Phe-HOMO-Phe-fluoromethyl ketone	*New
Substrates
C 3282	Z-Phe-Arg 4-methoxy-b-naphthylamide hydrochloride
Antibodies
C 2970	Monoclonal Anti-Cathepsin L

Ubiquitination