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The use of an insoluble polymer support greatly simplifies the synthesis of peptides, as after each repetitive coupling step, the purification of the growing peptide chain is accomplished by a simple filtration procedure. Its major advantage is, that after each reaction the corresponding soluble reagents and by-products are removed effectively from the retained polymer and the resin-bound macromolecules.
All resins for Solid Phase Peptide Synthesis offered by Sigma Aldrich are high quality, functionalized, gel-type, beaded supports with a broad variety of chemical architectures to meet the requirements of all common synthetic approaches. Our supports are offered in a wide variety of resin parameters such as chemical composition, degree of cross-linking, bead size, particle size distribution and capacity (amount of functionalities for anchoring amino acid residues or linker moieties).
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