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 CUSTOM SYNTHESIS

Custom stable isotope rich products for non-radioactive in vivo metabolic tracing and analysis

All products are minimum 99% CP unless otherwise indicated.


ISOTEC has the most experienced team of stable isotope custom synthesis chemists in the industry, led by impressive group of Ph.D.'s, each one an expert in his field. ISOTEC routinely engages in the multiple step syntheses of complex labeled molecules including, metabolites and steroids. On-site production capabilities and an inventory of basic starting materials enable us to provide rapid synthesis of new compounds. We can deliver your custom synthesis compound faster than any other company in our industry.

"Let us help you design your stable isotope labeled molecule!"   Please contact C.T. Tan PhD at: isosales@sial.com

We will synthesize quantities ranging from milligrams to kilograms, provide custom packaging services, and guarantee client confidentiality.


cGMP Capabilities

Our Synthesis Expertise Includes:
Alkylations Esterifications
Asymmetric Synthesis Friedel-Crafts Acylations
Biosynthesis Algae, Bacteria Gas Phase Chemistry
Brominations & Iodinations Grignard Reactions
Carbohydrate Chemistry High Temperature & Pressure Reactions
Carbonylations High Purity Distillations (Gases & Solvents)
Catalytic Reductions (High & Low Pressure) Optical Resolutions
Diazotizations Oxidation Reactions
Deils-Alder Reactions Phosgenations
Enzymatic Reactions Pyrolysis


Our Team
  • Ph.D. Scientists
  • Chemical Engineers
  • Masters, Bachelors-Level Chemists, and Technicians
  • Teams dedicated to custom synthesis
  • Teams dedicated to biochemistry and biosynthetic reactions
  • Individual technical support
  • Dedicated customer service & sales representatives

Scale & Capacity

Our Laboratory Houses:

  • Up to 50 liter glass reactors
  • Up to 20 liter rotary evaporators
  • 0.5, 1, 5 and 10 gallon high pressure reaction vessels up to 5000 psi
  • 20, 50 and 72 liter fractional distillation stills

ISOTEC uses controls throughout all production processes to minimize variation and ensure superior product QUALITY, the highest RELIABILITYand highest CONSISTENCY. Our analytical laboratory is equipped with a wide array of instrumentation and techniques including:

  • High-Field NMR
  • Mass Spectrometers
  • Gas Chromatography
  • UV/VIS
  • Gas Moisture
  • Ion Chromotography
  • pH-Conductivity
  • FTIR
  • Karl Fischer
  • HPLCs
  • GC/MS

Our synthesis team is comprised of an impressive group of experienced professionals who have performed thousands of custom synthesis projects including:

  • Pharmaceutical Intermediates
  • Biologically Active Molecules
  • Isotopically Labeled Reference Standards
  • Controlled Drug Standards (DEA)
  • NMR Reference Standards
  • Metabolites

Isotec's Analytical Capabilities Include:
  • Multi-thousand Products’ Analysis
  • Method Development
  • Method Validation
  • Qualitative/Quantitative Determination
  • In-Process Controls
  • Reference Standard Analysis
  • Gas Analysis
Key Resources

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Equipment, Supplies & Books

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Frequently Asked Questions

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Books of Interest

Informational Flyer


Custom Synthesis Brochure
(179 kb)


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