| Antioxidant and Free Radical Scavengers |
| Product # |
Product Name |
Application |
Add to Cart |
| A7250 |
N-Acetyl-L-cysteine Sigma Grade, ≥99% (TLC), powder |
Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. |
|
| A0278 |
L-Ascorbic acid crystalline, particle size 20-200 mesh |
Antioxidant. |
|
| A7506 |
L-Ascorbic acid reagent grade, crystalline, particle size ~325 mesh |
Antioxidant. |
|
| C0625 |
Caffeic acid ≥99% (HPLC), crystalline |
Identified as the active component of propolis, a honey bee hive product. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. Inhibits proliferation of transformed cells. |
|
| C8221 |
Caffeic acid phenethyl ester >97% (HPLC and TLC), powder |
Identified as the active component of propolis, a honey bee hive product. Found to be a specific inhibitor of the nuclear transcription factor, NF-kB. Inhibits proliferation of transformed cells. |
|
| C9750 |
β-Carotene Type I, synthetic, ~95% (UV), powder |
The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of free radical-initiated peroxidation in vitro. |
|
| C4582 |
β-Carotene Type II, from synthetic, ≥95% (HPLC), crystalline |
The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of free radical-initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant. |
|
| C0692 |
(−)-Catechin gallate ≥98% (HPLC), from green tea |
Antioxidant constituent of green tea. At µM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. It also inhibits aromatase activity, an enzyme that converts androgens to estrogen. |
|
| C3878 |
Chlorogenic acid ≥95% (titration) |
Antioxidant. |
|
| C6003 |
Chlorophyllin Sodium copper salt commercial grade |
Mixture of semisynthetic, water-soluble derivatives of chlorophyll. Shown to be an effective inhibitor of aflatoxin hepatocarcinogenesis in animal models by blocking carcinogen bioavailability. |
|
| C9008 |
p-Coumaric acid |
Phenol. |
|
| 43725 |
Delphinidin chloride purum, ≥95.0% (HPLC) |
Anthocyanin. Inhibits epidermal growth factor receptor in cancer cells. |
|
| D3525 |
Diosmin ~95% |
Flavonoid which has anti-inflammatory and chemopreventive characters. Inhibits chemical carcinogenesis in the bladder, esophagus and colon. |
|
| E2250 |
Ellagic acid ~95% (titration), powder, from tree bark |
Plant phenol that is a potent antioxidant presumably by acting as a scavenger of oxygen species produced by hydrogen peroxide treatment, and as a protector of the DNA double helix from alkylating agent injury. |
|
| E1753 |
(−)-Epicatechin ≥90% (HPLC) |
Antioxidant |
|
| E4018 |
(+)-Epicatechin from Green Tea ≥98% (HPLC) |
Antioxidant |
|
| E3893 |
(−)-Epicatechin gallate from Green Tea ≥98% (HPLC) |
Antioxidant |
|
| E4268 |
(−)-Epigallocatechin gallate from Green Tea ≥80% (HPLC) |
Tumor-inhibiting constituent of green tea. At µM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. |
|
| E4143 |
(−)-Epigallocatechin gallate from Green Tea ≥95% |
Tumor-inhibiting constituent of green tea. At µM concentrations, it inhibits VEGF-induced tyrosine phosphorylation. |
|
| E51791 |
Eugenol 99% |
COX-2 inhibitor. |
|
| 128708 |
Ferulic acid 99% |
Ferulic acid is an antioxidant which neutralizes free radicals (superoxide, nitric oxide and hydroxyl radical) which could cause oxidative damage of cell membranes and DNA. |
|
| G7384 |
Gallic acid |
Naturally occurring plant phenol. Induces apoptosis. |
|
| G6657 |
(−)-Gallocatechin >98% (HPLC) |
Possesses free radical scavenging ability. Inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells. |
|
| G6782 |
(−)-Gallocatechin gallate from Green Tea ≥98% (HPLC) |
Antioxidant |
|
| T0125 |
Tannic acid powder |
Inhibitor of CXCL12 (SDF-1α)/CXCR4 with antiangiogenic activity. |
|
| T3437 |
Tannic acid meets USP testing specifications |
Inhibitor of CXCL12 (SDF-1α)/CXCR4 with antiangiogenic activity. |
|
| G6910 |
Ginkgolide B from Ginkgo biloba leaves ~90% (HPLC) |
Inhibit platelet-activating factor and block the toxicity of amyloid-β1-42 or sPrP106. |
|
| H5254 |
Hesperidin ~80% |
Citrus bioflavonoid, decreases oxidative stress. |
|
| K0133 |
Kaempferol ≥90% (HPLC), powder |
A flavonol shown to revert the transformed phenotype of phorbol ester-treated mouse fibroblasts or v-H-ras-transformed NIH 3T3 cells. Induces significant nuclear DNA degradation concurrent with lipid peroxidation. |
|
| T5625 |
(±)-α-Lipoic acid synthetic, ≥99% (titration), powder |
Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. |
|
| L9283 |
Luteolin ≥98% (TLC), powder |
Hydroxylated flavone derivative, a strong anti-oxidant and radical scavenger. Suggested to play a role in prevention of cancer. |
|
| L9879 |
Lycopene from Tomato 90-95% |
Antioxidant micronutrient of tomatoes associated with decreased risk for cancer and cardiovascular disease. Enhances gap juction communication between cells via upregulation of connexin 43 and reduces proliferation of cancer cells in culture. |
|
| O5507 |
Linoleic acid, conjugated |
Potent inhibitor of breast, skin, and colon carcinogenesis and tumor cell proliferation; inhibits bFGF-induced endothelial cell proliferation; potent antioxidant. |
|
| O1008 |
Oleic acid reagent grade, ~99% (GC) |
Suppresses the levels of the oncogene for breast cancer. |
|
| Q0125 |
Quercetin Dihydrate ≥98% (HPLC), powder |
Flavonoid with anticancer activity. Mitochondrial ATPase and phosphodiesterase inhibitor. Inhibits PI3-kinase activity and slightly inhibits PIP Kinase activity. Has antiproliferative effects on cancer cell lines. |
|
| R5010 |
Resveratrol >99% (GC) |
Phenolic antioxidant found in grapes and peanuts that modulates lipid metabolism and inhibits platelet aggregation. May have chemopreventive action in prostate cancer related to its ability to inhibit androgen receptors. |
|
| R5143 |
Rutin Hydrate ≥95% (HPLC), powder |
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. |
|
| M6680 |
Se-(Methyl)selenocysteine Hydrochloride ≥95% (TLC) |
Chemopreventive agent that blocks cell cycle progression and proliferation of premalignant mammary lesions and induces apoptosis of cancer cell lines in culture. |
|
| S3132 |
Seleno-L-methionine ≥98% (TLC), powder |
Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks and mutations. |
|
| 214485 |
Sodium selenite 99% |
More potent than selenomethionine in reducing carcinogenesis. |
|
| T3634 |
(+)-α-Tocopherol from vegetable oil, Type V, ~1000 IU/g |
Antioxidant. |
|
| X6250 |
Xanthophyll from alfalfa |
Dietary carotenoid with no vitamin A potency. Increases macular pigment concentration in the eye and may improve visual function. |
|
|
|
| Product # |
Product Name |
Application |
Add to Cart |
| 855057 |
Betulinic acid technical grade, 90% |
Betulinic acid, a pentacyclic triterpene, selectively induces apoptosis in tumor cells by directly activating the mitochondrial pathway of apoptosis through a p53- and CD95-independent mechanism. |
|
| D2016 |
Biochanin A powder |
Flavonoid. Has estrogenic activity. Also has antioxidant, anticarcinogenic, anti-atherogenic and anti-osteoporotic activities. |
|
| B7777 |
Budesonide ≥99% |
Budesonide is a second generation glucocorticoid with low systemic absorption. It is used as an anti-inflammatory agent and shows inhibitory effects on benzo[a]pyrene-induced carcinogenesis of the lung in mice. |
|
| C0750 |
Caffeine ReagentPlus, powder |
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. |
|
| C80687 |
trans-Cinnamaldehyde 99% |
Has shown to have glutathione S-transferase inhibition in human melanoma cells, anti-tyrosinase, and ATPases inhibition activity. |
|
| I12603 |
β-Ionone 96% |
Isoprenoid. Suppresses the growth of cancer cell lines. |
|
| L9647 |
Limonin from citrus seeds, ≥75% (HPLC) |
Has anti-proliferative activity on human breast cancer cultured cells. Inhibited cancinogenesis in Chinese hamster bucal pouch. |
|
| L2378 |
γ-Linolenic acid ≥99%, liquid |
Inhibits the growth of tumors. |
|
| M6383 |
2-Methoxyestradiol crystalline |
Potent inhibitor of endothelial cell proliferation and angiogenesis. |
|
| N3395 |
Nomilin |
Has anti-proliferative activity on cultured human breast cancer cells. |
|
| O5504 |
Oleanolic acid ≥97% |
Anti-inflammatory and antihyperlipidemic properties. |
|
| 253731 |
Phenethyl isothiocyanate 99% |
Naturally occurring compound found in some cruciferous vegetables. |
|
| P7262 |
Plumbagin from Plumbago indica practical grade |
Exhibits cytotoxicity in rodent models of carcinogenesis and carcinoma; has antifungal, antiviral, and antibacterial action. |
|
| P5630 |
3,4-Dihydroxybenzoic acid |
Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase. |
|
| R7269 |
4,5-Dihydroxyanthraquinone-2-carboxylic acid |
Constituent that is enriched in rhubarb with anti-inflammatory, anti-osteoarthritic, and anti-cancer activity. Its mechanism of action is unknown, but it has been shown to reduce IL-1β production and secretion and caspase-3 activity. |
|
| S5890 |
Sanguinarine chloride Hydrate ≥98% (HPLC) |
A natural product with antimicrobial, anti-inflammatory, and anti-oxidant properties. Has antiproliferative, pro-apoptosis effects in some cancer cell lines. |
|
| S0292 |
Silymarin |
Mixture of anti-hepatotoxic flavonolignans from the fruit of Silybum marianum. |
|
|
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| Product # |
Product Name |
Application |
Add to Cart |
| N5757 |
α-Naphthoflavone |
Synthetic flavonoid. Inhibitor of P-450-mediated metabolism. |
|
|
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| Product # |
Product Name |
Application |
Add to Cart |
| E6510 |
Ergosterol ≥75% |
Phytosterol. Also called provitamin D2, is an unsaponifiable lipids. Converted to ergocalciferol (vitamin D2) upon irradiation by ultraviolet light or electronic bombardment. Antirachitic activity. |
|
| M0253 |
L-Mimosine from Koa hoale Seeds ≥98% |
A plant amino acid and potential inhibitor of the cell cycle giving rise to growth arrest in G1-phase. An iron chelator that inhibits DNA replication in mammalian cells. Has been shown to have apoptotic activity. |
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|
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| Product # |
Product Name |
Application |
Add to Cart |
| A7007 |
S-(5′-Adenosyl)-L-methionine chloride ~70%, from yeast (L-Methionine enriched) |
Methyl donor; cofactor for enzyme-catalyzed methylations. |
|
| F7876 |
Folic acid ~98% |
Enzyme cofactor essential for the synthesis, methylation, and repair of DNA. Folic acid supplements may reduce colorectal cancer risk. |
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| Product # |
Product Name |
Application |
Add to Cart |
| A1224 |
N-(4-Acetamidophenyl)indomethacinamide ≥98%, crystalline |
Potent and selective reversible COX-2 inhibitor. Shows anti-inflammatory, anti-angiogenic, and cancer chemopreventive activity in various experimental models. |
|
| A5376 |
Acetylsalicylic acid ≥99.0%, crystalline |
Blocks the production of prostaglandins by inhibiting cyclooxygenase (COX), with greater selectivity toward the COX-1 isoform. |
|
| B2515 |
L-Buthionine-sulfoximine ≥97% (TLC) |
Blocks cellular resistance to chemotherapy by inhibiting γ-glutamylcysteine synthetase, a key enzyme in glutathione biosynthesis. |
|
| C80105 |
Chrysin 97% |
Potent aromatase inihibitor. |
|
| E2250 |
Ellagic acid ~95% (titration), powder, from tree bark |
A naturally occurring plant phenol that is a potent antioxidant presumably by acting as a scavenger of oxygen species produced by hydrogen peroxide treatment and as a protector of the DNA double helix from alkylating agent injury. |
|
| E0516 |
Etodolac |
Non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX-1 and COX-2. |
|
| 163333 |
Geraniol 98% |
Natural antioxidant. |
|
| I7378 |
Indomethacin ≥99% (TLC) |
Cyclooxygenase (COX) inhibitor that is relatively selective for COX-1. |
|
| I7904 |
Indomethacin heptyl ester methyl acetate solution |
Potent cyclooxygenase-2 inhibitor. 1700 times greater activity against COX-2 than COX-1. |
|
| 183164 |
(R)-(+)-Limonene 97% |
A monoterpene that is a major component of orange peel oil. In mouse it has been shown to be chemopreventive against mammary, skin, liver, lung, and stomach cancers. |
|
| M2147 |
Mevinolin from Aspergillus sp. ≥98% (HPLC) |
Blocks the production of mevalonate, a critical compound in the production of cholesterol and isoprenoids. This product increases cellular resistance to anticancer agents such as doxorubicin. It induces apoptosis in myeloma cells. |
|
| N5893 |
(±)-Naringenin ~95% |
Flavonoid. Inhibits glucose uptake. |
|
| N194 |
NS-398 solid |
Selective cyclooxygenase-2 (COX-2) inhibitor. |
|
| P7083 |
(S)-(−)-Perillic acid |
Interferes with activity of p21ras and other small G proteins by inhibiting post-translational cysteine isoprenylation. |
|
| 218391 |
(S)-(−)-Perillyl alcohol 96% |
Cyclic monoterpene that causes G1 cell cycle arrest, induces apoptosis, and inhibits posttranslational modification of signal transduction proteins. |
|
| P5654 |
Piroxicam ≥98% (TLC) |
Cyclooxygenase inhibitor. Non-steroidal anti-inflamatory agent (NSAID) shown to be effective in the chomoprevention of colon cancer. |
|
| P5654 |
2,3,4,5,6-Pentafluorothiophenol 97% |
Cyclooxygenase inhibitor. Non-steroidal anti-inflamatory agent (NSAID) shown to be effective in the chomoprevention of colon cancer. |
|
| R2146 |
Radicicol from Diheterospora chlamydosporia solid |
Antifungal macrolactone antibiotic that inhibits protein tyrosine kinase. Radicicol induces the differentiation of HL-60 cells into macrophages, blocking cell cycle at G1 and G2. It suppresses NIH 3T3 cell transformation. |
|
| S0125 |
D-Saccharic acid Calcium salt Tetrahydrate |
Calcium glucarate is a constituent of many fruits (apples, citrus fruits) and cruciferous vegetables. Inhibits β-glucuronidase, a phase II enzyme that is elevated in some hormone-dependent cancers of the breast, prostate, and colon. |
|
| S0417 |
Silibinin |
Principal component of silymarine; flavonolignan that is chemopreventive against prostate and liver cancer. |
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| S3626 |
Squalene ≥98%, liquid |
Biosynthetic precursor to all steroids. Cytoprotective to normal cells exposed to carcinogens and anti-tumor agents. |
|
| S8139 |
Sulindac ≥99.0% |
A non-steroidal anti-inflammatory compound (NSAID) and preferential inhibitor of COX-1. Treatment of human colorectal cancer cell lines induces MRP-1 and MRP-3 but not other members of the MRP family. |
|
| S3131 |
Sulindac Sulfide |
A non-steroidal anti-inflammatory compound (NSAID) with preference for COX-1. Inhibits Ras activation of Raf-1; impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. Active metabolite of sulindac. |
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| S1438 |
Sulindac sulfone 99% (TLC), solid |
Metabolite of sulindac that inhibits cell growth by inducing apoptosis independently of cyclooxygenase inhibition. Inhibits the development and induces regression of premalignant adenomatous polyps. |
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| Product # |
Product Name |
Application |
Add to Cart |
| M5250 |
Melatonin powder |
Hormone postulated to mediate photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase; peroxynitrite scavenger. |
|
| R1402 |
Raloxifene Hydrochloride solid |
Selective estrogen receptor modulator (SERM); acts as an anti-estrogen in both breast and uterine tissue while being estrogenic in bone. May have efficacy against estrogen-sensitive cancers. |
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| T5648 |
Tamoxifen ≥99% |
Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. |
|
| T9262 |
Tamoxifen Citrate salt ≥99% |
Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. |
|
| S1270 |
β-Sitosterol synthetic, ≥95% |
Synthetic form of a plant derived estrogen. |
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| Product # |
Product Name |
Application |
Add to Cart |
| I7256 |
Indole-3-carbinol |
Inhibits cancinogenesis at the initiation stage. Has be shown to inhibit carcinogenesis in several animal species but enhances tumor incidence if administered at a post-initiation stage. Found in cruciferous vegetables. |
|
| L2037 |
β-Lapachone 98% (TLC) |
β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells. |
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| S0417 |
Silibinin |
Principal component of silymarine; flavonolignan that is chemopreventive against prostate and liver cancer. |
|
| U5127 |
Ursodeoxycholic acid ≥99% |
Suppresses COX-2 induction. |
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| Product # |
Product Name |
Application |
Add to Cart |
| N3633 |
β-Naphthoflavone 90-95% |
Inhibitor of P-450-mediated metabolism. |
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| Product # |
Product Name |
Application |
Add to Cart |
| O5504 |
Oleanolic acid ≥97% |
Anti-inflammatory and antihyperlipidemic properties. |
|
| U6753 |
Ursolic acid ≥90% |
Inhibits Cyclooxygenase-2 transcription. |
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| Product # |
Product Name |
Application |
Add to Cart |
| B1253 |
Butylated hydroxyanisole |
Synthetic phenolic antioxidants. Shown to inhibit carcinogenicity in a variety of carcinogen-induced tumor models. |
|
| B1378 |
2,6-Di-tert-butyl-4-methylphenol ≥99% (GC), powder |
Butylated hydroxytoluene (BHT) is a phenolic antioxidant. It has been shown to inhibit lipid peroxidation. It causes lung injury and promotes tumors in mice, but this may be due to a metabolite of BHT. |
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| C1305 |
Cafestol acetate ≥98% |
One of the components of coffee shown to be chemopreventive for colorectal cancer. |
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| F8509 |
Fumaric acid cell culture tested, insect cell culture tested |
Common metabolic intermediate in the citric acid and urea cycles in mammalian cells. Antioxidant and acidulant. |
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| K1755 |
Kahweol ≥95% |
Inducer of glutathione S-transferase (GST) and therefore may be a cancer chemoprevetative agent. |
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| S6317 |
L-Sulforaphane ≥98% (GC), liquid |
Potent, selective inducer of phase II detoxification enzymes with anticarcinogenic properties. Occurs naturally in broccoli. |
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| Product # |
Product Name |
Application |
Add to Cart |
| A3145 |
Apigenin ~95% (TLC), from parsley, powder |
Plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53. |
|
| 465119 |
Baicalein 98% |
The flavonoid component of Nepalese and Sino-Japanese crude drugs.1 Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation. |
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| D2016 |
Biochanin A powder |
An isoflavone with anticancer proliferation, differentiation and chemopreventitive properties. Inhibits metabolic activation of benzo[a]pyrene. |
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| C80105 |
Chrysin 97% |
A flavone which inhibits metabolic activation of benzo[a]pyrene. |
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| D7802 |
Daidzein ≥98%, synthetic |
A phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. Arrests cell cycle at G1 in Swiss 3T3 cells. |
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| F4043 |
Fisetin |
Flavonol, inhibits TH2-type cytokine production by activated human basophils. |
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| G6776 |
Genistein from Glycine max (soybean), ~98% (HPLC) |
Phytoestrogen from soybean that is an inhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Anti-angiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. |
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| G6649 |
Genistein synthetic, ≥98% (HPLC), powder |
Phytoestrogen from soybean that is an inhibitor of tyrosine protein kinase; competitive inhibitor of ATP in other protein kinase reactions. Anti-angiogenic agent, down-regulates the transcription of genes involved in controlling angiogenesis. |
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| K0133 |
Kaempferol ≥90% (HPLC), powder |
A flavonol shown to revert the transformed phenotype of phorbol ester-treated mouse fibroblasts or v-H-ras-transformed NIH 3T3 cells. Induces significant nuclear DNA degradation concurrent with lipid peroxidation. |
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| Q0125 |
Quercetin Dihydrate ≥98% (HPLC), powder |
Flavonoid with anti-cancer activity. Mitochondrial ATPase and phosphodiesterase inhibitor. Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Has antiproliferative effects on cancer cell lines. |
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| S1270 |
β-Sitosterol synthetic, ≥95% |
Synthetic form of a plant derived estrogen. |
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| Z2125 |
Zearalenone |
Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. |
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