Celltransmissions, Volume 19, No. 4

In this issue: Main Article: Corticotropin-Releasing Factor Antagonists: Potential Novel Therapies for Human Disease Dimitri E. Grigoriadis New Products Click here to request Celltransmissions Click to download Celltransmissions Vol. 19, No. 4 Click for back issues of Celltransmissions

Product Highlights:

• Assay Kits for Cell Signaling
• RS-102895: A CCR2b chemokine receptor antagonist
• Cinalukast (Ro 24-5913): Subtype selective, orally active, cysteinyl leukotriene (CysLT₁) receptor antagonis
  First available from Sigma-RBI!
• NPS 2390: A potent and selective noncompetitive Group I metabotropic glutamate (mGlu) receptor antagonist
  First available from Sigma-RBI!
• Reboxetine mesylate: A selective norepinephrine reuptake inhibitor (SNRI)
• Deguelin: An inhibitor of activated Akt with chemopreventive properties
• Protease-Activated Receptor (PAR) Modifying Peptides
• Anti-ASAP1/Centaurin b4: A marker for ADP-ribosylation factor GTPase activating protein (ARF-GAP)
• HA 14-1: A cell-permeable, nonpeptide apoptosis inducer and Bcl-2 antagonist
• Antibodies to Multi-Drug Resistance Associated Proteins (MRPs)
• Monoclonal Antibody to NEDD8: A ubiquitin-like protein marker
• SCH 58261: A potent and selective non-xanthine A_2A adenosine receptor antagonist
• Ligand-Sets™ for Assay Validation & High Throughput Screening
• LOPAC^1280™ Library for Assay Validation & High Throughput Screening