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Sigma has a wide portfolio of products to support Epigenetics research. The Imprint™ Bisulfite Modification Kit is a rapid method to determine the methylation status of CpG islands. The Imprint Chromatin Immunoprecipitation Kit provides the perfect blend of speed and performance for the investigation of protein-DNA interactions in vivo. Sigma also has products to study Histone modification, including transcription regulators such as anti-histone antibodies.


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  • The Imprint Chromatin Immunoprecipitation Kit
    The fastest and most convenient ChIP kit available

    • Fast - Total protocol time of less than 6 hours, making the Imprint kit the fastest on the marketing
    • Sensitive - As few as 20,000 cells required for each ChIP sample
    • Convenient - fewest steps of any available ChIP protocol
    • Flexible - Protocols for cells or tissue, and convenient strip-well format for high throughput applications.
    • Complete - includes columns and reagents for DNA purification as well as an integrated protocol for amplification with the GenomePlex technology
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