MISSION® shRNA Gene Family Sets

The MISSION® TRC shRNA gene family sets are collections of genes related to specific functional classes. The format is designed for target discovery and pathway analysis. All of the gene family sets can be utilized without the need for robotics equipment. A dedicated researcher with a multichannel pipette can successfully utilize these gene family sets to discover novel small molecule targets and gene regulators. All gene family sets are pre-arrayed in 96-well plate formats, and are selected utilizing multiple databases including the NCBI, GO database, protein lounge, and Ingenuity. All human gene family sets are available as bacterial stocks, purified DNA, or lentiviral particles. The murine gene family sets are only available as bacterial stocks.

MISSION shRNA Gene Family Sets
Human Gene Family Sets	Product Numbers			Product Information		Supporting Products
	Bacterial Stocks	Purified DNA	Lentiviral Particles	Genes	Clones*	Antibodies	Peptides and Purified Proteins	siRNA	Small Molecule Agonists and Antagonists
Apoptosis Pathway	SH1911	SH1921	SH1931	437	2074	481	119	7396	420
B-Cell Activation	SH2911	SH2921	SH2931	99	534	93	20	1419	126
Cell Adhesion Genes	SH2211	SH2221	SH2231	366	1965	217	55	5942	100
Cytokine and Chemokine Receptors	SH1311	SH1321	SH1331	97	459	69	17	1440	6
Cytokines and Chemokines	SH0811	SH0821	SH0831	106	502	70	41	1405	50
Cytoskeleton Genes	SH2311	SH2321	SH2331	273	1462	215	20	4588	65
DNA Repair Pathway	SH1811	SH1821	SH1831	117	647	44	2	1815	44
Epigenetic Regulators	SH3011	SH3021	SH3031	10	50	6	1	1593	2
Extracellular Matrix Genes	SH2511	SH2521	SH2531	330	1657	3	1	200	58
G-Protein Coupled Receptors	SH0211	SH0221	SH0231	479	1997	171	42	4842	52
Helicases	SH2611	SH2621	SH2631	133	669	175	88	6002	1673
Ion Channels	SH1011	SH1021	SH1031	285	1056	16	1	1700	0
JAK-STAT pathway	SH2711	SH2721	SH2731	190	1123	152	101	4402	840
Kinases	SH0111	SH0121	SH0131	622	2855	177	45	2697	104
Nuclear Hormone Receptors	SH1111	SH1121	SH1131	46	209	292	67	9075	321
p53 Pathway	SH2411	SH2421	SH2431	239	1410	24	2	880	218
Phosphatases	SH0411	SH0421	SH0431	180	735	230	46	3952	139
T-Cell Activation	SH2811	SH2821	SH2831	241	1262	14	0	2455	0
Tumor Suppressors	SH0511	SH0521	SH0531	74	337	223	56	3597	142
Ubiquitin Hydrolases (DUBS)	SH0711	SH0721	SH0731	112	615	60	4	1263	8
Ubiquitin Ligases (E1,E2,E3)	SH2111	SH2121	SH2131	203	1018	72	11	1280	0

*The MISSION production and bio-informatics team constantly reviews and quality controls clones available for a gene family set. These numbers are very close to the actual number that will be shipped, but each researcher will receive a final plate map indicating the location and exact TRCN clone numbers.

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Murine Gene Family Sets	Product Numbers			Product Information		Supporting Products
	Bacterial Stocks	Purified DNA	Lentiviral Particles	Genes	Clones*	Antibodies	Peptides and Purified Proteins	siRNA	Small Molecule Agonists and Antagonists
Tyrosine Kinase	SM2011	NA	NA	109	518	17	6	3324	0
Phosphatase	SM0411	NA	NA	220	1110	109	28	1490	109

*The MISSION production and bio-informatics team constantly reviews and quality controls clones available for a gene family set. These numbers are very close to the actual number that will be shipped, but each researcher will receive a final plate map indicating the location and exact TRCN clone numbers.

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Additional resources for ion channels research.

Additional sets will be made available over the coming months. If your gene set of interest is not yet available, please inquire for advanced custom preparation at RNAi@sial.com. We can assemble custom gene sets at any time.

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Contact Us
For questions about the library, pricing and quotes or other concerns, please e-mail us at: RNAi@sial.com.

MISSION is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. Label License.

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