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Your Favorite Gene - Search
Life Science Innovations
PathFinder

 Pre-arrayed siRNA Libraries

siRNA
 
MISSION siRNA

MISSION siRNA Libraries offer the most compelling siRNA collections for high-throughput screening by targeting genes of high therapeutic value as defined with input from major pharmaceutical companies. The flexible format of MISSION siRNA libraries facilitates research for life scientists who are interested in specific classes of genes as well as those who need to generate information across the entire druggable genome.

Great Introductory Discounts Available on all MISSION siRNA Libraries
Request a quote today at RNAi@sial.com


Benefits of MISSION siRNA Libraries:
  • siRNA designed using the powerful Rosetta siRNA Design Algorithm, providing for more efficient gene knockdown and greater target specificity
  • 3 individual siRNA provided per gene, allowing for optional siRNA pooling steps
  • siRNA provided at quantities to allow for multiple screenings and hit follow-up
  • Gene targets picked in collaboration with major pharmaceutical company, and based on latest NCBI classifications


MISSION siRNA Library Format:
  • 21mer siRNA duplexes with TT overhangs
  • 3 individual siRNA duplexes per target gene
  • All siRNA duplexes spotted in 96 well microplates with 80 duplexes per plate. First and last columns of each plate are empty.
  • Control siRNA sequences included on all plates
Ordering MISSION siRNA for Single Gene Targets

We've made ordering MISSION siRNA for single gene targets easy through Sigma's state-of-the-art web interface,
Your Favorite Gene.

Your Favorite Gene Search

To find a MISSION siRNA that knocks down your gene, simply search on your gene of interest by gene name, symbol, RefSeq, or Gene ID number.



Great Introductory Discounts Available on all MISSION siRNA Libraries
Request a quote today at RNAi@sial.com


Ordering Information

MISSION siRNA Human Druggable Genome

MISSION siRNA Rat Druggable Genome

MISSION siRNA Mouse Kinase Library


Sample Data

Silencing efficacy of representative MISSION siRNAs designed using the Rosetta algorithm
Click Image to View Figure in its Entirety

Figure 1: Silencing Efficacy of 20 MISSION® siRNAs designed using the Rosetta algorithm. Target mRNA levels were measured by Quantigene from samples harvested 24 hr after transfection into HeLa cells.






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Contact Us
For questions about the library, pricing and quotes or other concerns, please e-mail us at: RNAi@sial.com.



MISSION is a registered trademark of Sigma-Aldrich Biotechnology LP and Sigma-Aldrich Co. Label License.



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