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 Panorama® Signal Transduction Functional Protein Array

Arrays
 

The Panorama Signal Transduction Functional Protein Array eases the process of identifying cellular response to external signals. Based on a proprietary tagging technology that ensures only functional proteins are immobilized, our comprehensive analysis system enables high throughput analysis against 259 human cell signaling proteins.

  • Full-length representation of 259 human signaling proteins involved in cell proliferation, cell differentiation and cell death
  • Probe with DNA, proteins, kinases or small molecules
  • Complete analysis system including buffers, techware, and software

Functional Array Technology

Slide Analysis Software (84.2 Kb GAL file)

Slide Analysis Template (4.71 Mb Excel file)

Signal Transduction Array Content


Order Information

Catalog Number Product Description Technical
Bulletin
HPFM4 Panorama® Human Protein Array-Signal Transduction

  Kit Contents:

  • Signal Transduction Protein
    Array - 2 ea
  • BCR-peptide - Cy™5
  • Monoclonal Anti-c-Myc-Cy™3 Conjugate
  • Cover slips
  • quadiPERM® Vessel
  • 50 mL Conicol - 2 ea
  • Pap Jar - 4 ea
  • Assay Buffer
  • Functional Buffer
  • CHAPS
  • BSA
  • 1M DTT
  • Signal Transduction CD (GAL file and analysis spreadsheet)


Signal Transduction Array Content:

Symbol Gene Name Entrez Gene ID
ABI1
Ab1 interactor 1
10006
ACVR1
activin A receptor, type I
90
ADD1
adducin 1 (alpha)
118
ADRBK2
adrenergic, beta, receptor kinase 2
157
AKT1
v-akt murine thymoma viral oncogene homolog 1
207
AMD1
adenosylmethionine decarboxylase 1
262
ANXA1
annexin A1
301
APEX1
APEX nuclease (multifunctional DNA repair enzyme)
328
ARAF1
v-raf murine sarcoma 3611 viral oncogene homolog 1
369
ARHA
ras homolog gene family, member A
387
ARRB1
arrestin, beta 1, transcript variant 1
408
ATF3
activating transcription factor 3
467
ATF4
activating transcription factor 4 (tax-responsive enhancer element B67)
468
BAD
BCL2-antagonist of cell death
572
BCL10
B cell lymphoma/leukemia 10
8915
BCL2A1
BCL2-related protein A1
597
BDNF
brain-derived neurotrophic factor, transcript variant 5
627
BIRC2
baculoviral IAP repeat-containing 2
329
BIRC3
baculoviral IAP repeat-containing protein 3
330
BIRC5
baculoviral IAP repeat-containing 5 (survivin)
332
BLK
B lymphoid tyrosine kinase
640
BMP7
bone morphogenetic protein 7 (osteogenic protein 1)
655
BMPR1A
bone morphogenetic protein receptor, type IA
657
BMX
BMX non-receptor tyrosine kinase
660
BRD8
bromodomain containing 8
10902
BTRC
beta-transducin repeat containing, transcript variant 1
8945
BUB1B
BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast)
701
CA1
carbonic anhydrase I
759
CALM1
calmodulin 1 (phosphorylase kinase, delta)
801
CALM2
calmodulin 2 (phosphorylase kinase, delta)
805
CALM3
calmodulin 3 (phosphorylase kinase, delta)
808
CAMK2B
calcium/calmodulin-dependent protein kinase (CaM kinase) II beta
816
CAMK2G
calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma
818
CAMK4
calcium/calmodulin-dependent protein kinase IV
814
CAMKK2
calcium/calmodulin-dependent protein kinase kinase 2, beta
10645
CASP3
caspase 3, apoptosis-related cysteine protease
836
CASP9
caspase 9, apoptosis-related cysteine protease
842
CCNB1
cyclin B1
891
CCND1
cyclin D1 (PRAD1: parathyroid adenomatosis 1)
595
CCND2
cyclin D2
894
CCNH
cyclin H
902
CDC2
cell division cycle 2, G1 to S and G2 to M
983
CDC20
CDC20 cell division cycle 20 homolog (S. cerevisiae)
991
CDC25A
cell division cycle 25A
993
CDC25B
cell division cycle 25B
994
CDC25C
cell division cycle 25C
995
CDC42
cell division cycle 42 (GTP binding protein, 25kDa)
998
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
1026
CDKN2B
cyclin-dependent kinase inhibitor 2B
1030
CDKN2C
cyclin-dependent kinase inhibitor 2C
1031
CDKN2D
cyclin-dependent kinase inhibitor 2D
1032
CGEF2
cAMP-regulated guanine nucleotide exchange factor II
11069
CHN1
chimerin (chimaerin) 1
1123
CISH
cytokine inducible SH2-containing protein
1154
CNN1
calponin 1, basic, smooth muscle
1264
CREB1
cAMP responsive element binding protein 1
1385
CSEN
calsenilin, presenilin binding protein, EF hand transcription factor
30818
CSNK1D
casein kinase 1
1453
CSNK1G1
BC017236, casein kinase 1
53944
CSNK1G2
casein kinase 1
1455
CSNK2A1
casein kinase 2, alpha 1 polypeptide
1457
CSNK2A2
casein kinase 2, alpha prime polypeptide
1459
CSTB
cystatin B (stefin B)
1476
CTNNB1
Beta-catenin
1499
DDB1
damage-specific DNA binding protein 1
1642
DDIT3
DNA-damage-inducible
1649
DNAJB1
DnaJ (Hsp40) homolog, subfamily B
3337
DR1
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
1810
DSCR1
Down syndrome critical region gene 1
1827
DUSP6
dual specificity phosphatase 6
1848
DVL2
dishevelled, dsh homolog 2 (Drosophila)
1856
EEF1A1
eukaryotic translation elongation factor 1 alpha 1
1915
EFS
embryonal Fyn-associated substrate
10278
EGR2
early growth response 2 (Krox-20 homolog, Drosophila)
1959
EIF4E
eukaryotic translation initiation factor 4E
1977
EIF4EBP1
eukaryotic translation initiation factor 4E binding protein 1
1978
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
2004
EMS1
ems1 sequence (mammary tumor and squamous cell carcinoma-associated)
2017
ENO1
enolase 1
2023
ENO2
enolase 2
2026
EPS15
epidermal growth factor receptor substrate 15
2060
ERG
transcriptional regulator ERG
2078
ESR2
estrogen receptor 2 (ER beta)
2100
ETS2
v-ets erythroblastosis virus E26 oncogene homolog 2
2114
EXT1
exostoses (multiple) 1
2131
EXT2
exostoses (multiple) 2
2132
EZH2
enhancer of zeste homolog 2 (Drosophila)
2146
FADD
Fas (TNFRSF6)-associated via death domain
8722
FEN1
flap structure-specific endonuclease 1
2237
FES
feline sarcoma oncogene
2242
FGF1
fibroblast growth factor 1 (acidic)
2246
FGF13
fibroblast growth factor 13
2258
FOLH1
folate hydrolase (prostate-specific membrane antigen) 1
2346
FRK
fyn-related kinase
2444
FYN
FYN oncogene related to SRC, FGR, YES
2534
GADD45G
growth arrest and DNA-damage-inducible
10912
GATA3
GATA binding protein 3
2625
GCLC
glutamate-cysteine ligase, catalytic subunit
2729
GEM
GTP binding protein overexpressed in skeletal muscle
2669
GNA15
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
2769
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
2771
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
2773
GNA01
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide O
2775
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
2781
GNB1
guanine nucleotide binding protein (G protein), beta polypeptide 1
2782
GNB3
guanine nucleotide binding protein (G protein), beta polypeptide 3
2784
GNG11
guanine nucleotide binding protein (G protein), gamma 11
2791
GNG2
guanine nucleotide binding protein (G protein), gamma 2
54331
GNG3
guanine nucleotide binding protein (G protein), gamma 3
2785
GNG4
guanine nucleotide binding protein (G protein), gamma 4
2786
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
2792
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
2793
GOLGA5
golgi autoantigen, golgin subfamily a
9950
GPRK6
G protein-coupled receptor kinase 6
2870
GRB10
growth factor receptor-bound protein 10
2887
GRB2
growth factor receptor-bound protein 2
2885
GSK3B
glycogen synthase kinase 3 beta
2932
HBG1
hemoglobin, gamma A
3047
HCLS1
hematopoietic cell-specific Lyn substrate 1
3059
HIF1A
hypoxia-inducible factor 1, alpha subunit
3091
HIF3A
hypoxia inducible factor 3, alpha subunit
64344
HIST1H4I
histone 1, H4i
8294
HK1
hexokinase 1
3098
HMGB2
high-mobility group box 2
3148
HPRT1
hypoxanthine phosphoribosyltransferase 1 (Lesch-Nyhan syndrome)
3251
HRAS
v-Ha-ras Harvey rat sarcoma viral oncogene homolog
3265
HSPA1A
heat shock 70kDa protein 1A
3303
HSPCA
heat shock 90kDa protein 1, alpha
3320
HUS1
HUS1 checkpoint homolog
3364
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
3397
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
3398
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells
3551
IL18
interleukin 18
3606