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 Anhydrous and BioTech Solvents

Solvents
 

Sigma-Aldrich's offers a full range of high-purity solvents with extremely low water levels specifically manufactured for moisture sensitive Organic and BioTech applications.


Anhydrous Solvents
BioTech Solvents
Sigma-Aldrich Anhydrous & BioTech Solvents Table




Anhydrous Solvents
  Use our anhydrous solvent supplier cross-reference guide to compare grades and packaging options with Sigma-Aldrich quality products. (180 Kb PDF)

Complete list of Anhydrous grade solvents

Water content ranges from typically 10 to 30 ppm and do not require additional drying in your lab due to our low residue levels.


Ideal use in applications requiring extremely low levels of water such as:


Chemical Synthesis

High Throughput Screening

Oligonucleotide Synthesis

Organometallic


Sigma-Aldrich Anhydrous solvents are available in Sure/Seal Bottles and Pure-Pac containers.


Anhydrous 2-Methyltetrahydrofuran - A versatile alternative to Tetrahydrofuran and Dichloromethane

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BioTech Solvents

Complete list of BioTech grade solvents


The BioTech line of solvents is characterized by not only low water content, but also minimal residue and clean UV spectra.


Purified for biotechnology applications such as:


Peptide Synthesis

Oligonucleotide Synthesis

Protein Sequencing


Sigma-Aldrich BioTech solvents are available in Sure/Seal Bottles and Pure-Pac containers.

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Sigma-Aldrich Anhydrous & BioTech Solvents Table


Anhydrous Biotech
Acetonitrile  
Purity
Water
100 mL
Residue
27,100-4
99.8%
< 10 ppm
< 50 ppm
< 0.0005%
  49,444-5
≥99.93%
< 10 ppm
 
<0.0002%
UV nm
190
210
220
235-400
<0.008 meq/g
<0.0006 meq/g
Max Abs.
1.000
0.030
0.010
0.005
Titr. Acid
Titr. Base
Buytl acetate  
Purity
Water
Residue
28,772-5
≥99%
< 50 ppm
< 0.0005%
  49,616-2
99.7%
< 10 ppm
<0.0005%
UV nm


<0.0016 meq/g
Max Abs.


Titr. Acid
Carbon tetrachloride  
Purity
Water
100 mL
Residue
28,911-6
≥99.5%
< 20 ppm
<50 ppm
< 0.0003%
       
1-Chlorobutane  
Purity
Water
100 mL
Residue
41,425-5
99.5%
< 30 ppm
< 50 ppm
< 0.0005%
  49,617-0
≥99.5%
< 10 ppm

<0.0003%
UV nm



<0.0016 meq/g
Max Abs.



Titr. Acid
Chloroform
0.5-1.0% ethanol as stabilizer
 
Purity
Water
100 mL
Residue
40,176-5
99.7%
< 10 ppm
< 50 ppm
< 0.0005%
  49,618-9
≥99.9%
< 10 ppm

<0.0003%
   
Dichloromethane
50-150 ppm hydrocarbon as stabilizer
 
Purity
Water
100 mL
Residue
27,099-7
99.0%
< 10 ppm
< 50 ppm
< 0.0005%
  49,445-3
99.9%
< 20 ppm

<0.0003%
UV nm
235
240
250
260
340-400
Max Abs.
1.000
0.200
0.050
0.020
0.010
N,N-Diisopropylethylamine  
Purity
Water
Residue
27,101-2
99.8%
< 50 ppm
< 0.0001%
  49,621-9
99.5%
< 20 ppm
   
N,N-Dimethylformamide  
Purity
Water
Residue
22,705-6
99.8%
< 50 ppm
< 0.0005%
  49,448-8
≥99.9%
< 50 ppm
<0.0005%
UV nm
275
295
310
340-400
<0.0005 meq/g
<0.0003 meq/g
Max Abs.
0.30
0.10
0.05
0.07
Titr. Acid
Titr. Base
Dimethyl sulfoxide  
Purity
Water
Residue
27,685-5
≥99.9%
< 50 ppm
< 0.0005%
  49,442-9
99.8%
< 50 ppm
<0.0005%
UV nm
270
280
295
350-400
Max Abs.
1.00
0.30
0.10
0.01
1,4-Dioxane  
Purity
Water
100 mL
Residue
29,630-9
99.8%
< 30 ppm
< 50 ppm
< 0.0003%
       
Ether
1 ppm BHT as stabilzer
 
Purity
Water
100 mL
Residue
29,608-2
≥ 99.7%
< 30 ppm
< 50 ppm
< 0.0003%
       
Ethyl actate  
Purity
Water
Residue
27,098-9
99.8%
< 50 ppm
< 0.0005%
  49,451-8
≥99.8%
< 10 ppm
<0.0003%
UV nm
254
263
275-400
<0.0009 meq/g
Max Abs.
1.00
0.05
0.01
Titr. Acid
Heptane  
Purity
Water
100 mL
Residue
24,665-4
99%
< 10 ppm
< 50 ppm
< 0.0005%
  49,452-6
≥99%
< 50 ppm

<0.0002%
UV nm
197
210
220
230
260-400
Max Abs.
1.00
0.40
0.15
0.05
0.01
Methanol  
Purity
Water
100 mL
Residue
32,241-5
99.8%
< 20 ppm
< 50 ppm
< 0.0003%
  49,443-7
99.93%
< 20 ppm

<0.0003%
UV nm
203
220
230
240
260-400
<0.0003 meq/g
<0.0002 meq/g
Max Abs.
1.00
0.60
0.15
0.05
0.01
Titr. Acid
Titr. Base
3-Methyl-1-butanol  
Purity
Water
100 mL
Residue
30,943-5
≥99%
< 30 ppm
< 50 ppm
< 0.0005%
  49,620-0
≥99%
< 50 ppm

<0.0005%
UV nm


<0.002 meq/g
<0.1%
Max Abs.


Titr. Acid
Carbonyl
1-Methyl-2-pyrrolidinone  
Purity
Water
32,863-4
99.5%
< 50 ppm
  49,449-6
≥99.5%
< 50 ppm
UV nm
285
300
325
350-400
<0.01% meq/g
Max Abs.
1.00
0.50
0.10
0.01
Free amines
1-Propanol  
Purity
Water
Residue
27,954-4
99.7%
< 50 ppm
< 0.0003%
  49,619-7
99.7%

<0.0003%
UV nm


<0.0004 meq/g
Max Abs.


Titr. Acid
Pyridine  
Purity
Water
100 mL
Residue
27,097-0
99.8%
< 30 ppm
< 50 ppm
< 0.0005%
  49,441-0
≥99.9%
< 30 ppm

<0.0003%
UV nm
<0.001%
<0.0005%
<0.002%
<0.0001%
Max Abs.
Cl
Cu
NH3
SO4
Tetrahydrofuran
Inhibitor-free
 
Purity
Water
100 mL
Residue
401757
99.9%
< 20 ppm
< 50 ppm
< 0.0005%
  49,446-1
≥99.9%
< 50 ppm

<0.0005%
UV nm


<0.005%
Max Abs.


Peroxides
Tetrahydrofuran
250 ppm BHT as stabilizer
 
Purity
Water
100 mL
186562
99.9%
< 20 ppm
< 50 ppm
   
 
   
Toluene  
Purity
Water
100 mL
Residue
24,451-1
99.8%
< 10 ppm
< 50 ppm
<0.0005%
   
 
   

Visit the complete list of Sigma-Aldrich Anydrous Grade Solvents and Biotech Grade Solvents.

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