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 PEPscreen®: Custom Peptide Libraries

Custom Peptide Synthesis
 

Sigma has developed a new proprietary synthesis platform using state of the art technology.  This technology provides a solution to enhance your peptide screening applications.  As a result, large numbers of peptides are delivered quickly and affordably, offering great value for your money.

MALDI-TOF mass spec is run on 100% of your samples. 
Pass/Fail criteria of product is based on the specification that the desired product by mass spec must be presented as a major ion.  If the desired product is not a major ion, the peptide will be remade one additional time.   Mass spec images are saved as pdf files and burned onto a disc. You will receive a disc containing mass spec images for all successful peptides produced.

  • Yield: ~0.5-2mg
  • Average Purity: ~70% (based on 15mer sequences)
  • Length: 6-20 amino acid sequences
  • MALDI-TOF Mass Spectrometry on 100% of peptides
  • Peptides supplied lyophilized and in 96-well format (2-D bar coded tubes)
  • Delivery: ~7 working days (including time for remaking "failed" peptides)
  • Minimum order size is 24 peptides

NOW OFFERING MODIFICATIONS
N-terminal biotinylation
N-terminal acetylation
Non-standard residue incorporation
Disulfide bridge formation (cyclization)
C-terminal amidation

Internal Testing of Synthesis Platform:
We routinely run tests of this platform to ensure the quality of the product.
Average Crude Purity of 10mers: ~86%
Average Crude Purity of 15mers: ~73%
Average Crude Purity of 20mers: ~61%
Purity of ACP peptide at different positions on a 96-well plate: ~92% +/- 2%


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