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Specifications
- Peptide amounts from 2 mg to 10 g
- Sequence length of 5-50 amino acids
- Purity levels include Immunological Grade (>50%), >70%, >80% and >95%
- Comprehensive modification offering
- QC includes MALDI-TOF mass spectrometry and reversed phase HPLC
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Technical Design Analysis
- Aggregation potential
- Hydrophobicity at pH2 and pH6.8
- Peptide Stability
- Antigen Design: hydrophilicity, flexibility, secondary structure, conjugation chemistry
- Sequence Analysis and Peptide Design
Peptide Synthesis & Synthesis Instrumentation
- Patented segmented continuous-flow synthesis platform (Pepticus technology)
- Internal engineering for 24hour instrumentation maintenance support
- Synthesis is performed using Fmoc chemistry and a solid support resin
- Peptides are synthesized from C-terminus to N-terminus
Quality Control / Quality Assurance
- MALDI-ToF mass spectrometry verifies peptide composition
- Reversed phase HPLC illustrates peptide purity
- Amino Acid Analysis (AAA) available upon request for product composition and determining the net peptide content in the sample.
- Peptides are supplied lyophilized and amounts given in gross weight
- Specifications of each peptide are monitored and released for shipping by a professional within our Quality Assurance team.
Purification & Post Purification Quality Control
- Samples containing peptide impurities are purified by reversed phase chromatography.
- Multiple peak fractions are collected during the purification process
- Mass spectrometry and analytical HPLC on purified fractions
- An aliquot of the fractions possessing the desired molecular weight and purity are pooled together
- Mass spectrometry and analytical HPLC is performed on the combined aliquot
- After QC confirms that the aliquot of the combined fractions meet the specifications of the order, the fractions are physically combined into one sample
- Final mass spectrometry and HPLC analyses are performed on the combined sample.
Shipping & Dispatch Guidelines
- Dispatch time is dependent on complexity of the peptide sequence
- Estimated dispatch times
- Customer is notified if product will be delayed
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