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| Discovery Zr-PBD HPLC columns |
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| Discovery Zr-PBD consists of spherical, porous zirconia
particles with a durable coating of polybutadiene. It operates via reversed-phase
and ion-exchange modes. Discovery Zr-PBD complements the selectivity offering of the
other zirconia-, silica-, and polymer-based Discovery phases, and allows
the use of the full range of mobile phase pH from pH 1 to 13. |
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| Particle: |
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Zirconia (ZrO2) |
| Bonded Phase: |
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Polybutadiene |
| Particle Shape: |
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Spherical |
| Particle Size: |
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3 and 5µm |
| Pore Size: |
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300Å |
| Surface Area: |
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30m2/g |
| pH Range: |
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1 to 13 |
| Temperature
Range: |
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up to 100°C in standard hardware
(up to 150°C in custom all-steel hardware) |
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| Unique retention and selectivity for method development
at pH and temperature extremes |
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| • |
Good for bases, amines |
| • |
Similar to ODS-silica |
| • |
pH stable from 1-13 |
| • |
Thermally stable up to 100°C or higher |
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| FAST, HIGH pH, HIGH TEMPERATURE SEPARATIONS |
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| A significant difference between Discovery Zr-PBD and C18-silica
is that it can be used with basic pH mobile phases and elevated temperatures
where basic analytes have better peak shape and higher efficiency. This
is demonstrated in the separation of basic antihistamine compounds in the
figure below. |
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| EXCELLENT FOR BASIC COMPOUNDS |
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| Another example of the utility of Discovery Zr-PBD for
basic compounds is shown in the separation of tricyclic antidepressants
in the figure below. |
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