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RNAi Opportunities
Lentiviral delivery technology
Patent (364 Kb PDF)
Sigma-Aldrich Corporation is the exclusive worldwide licensee of U.S. Pat. Nos. 5,817,491; 5,591,624; 5,716,832; 6,312,682; 6,669,936; 6,235,522; 6,924,123 and foreign equivalents from Oxford Biomedica Ltd., Oxford, UK.
DNA-directed RNA interference
Patent (56 Kb PDF)
Sigma-Aldrich Corporation is also the exclusive worldwide licensee for certain fields of U.S. Pat. No. 6,573,099 and foreign counterparts co-owned by Benitec Australia, Ltd. and the Australian Commonwealth Scientific and Industrial Research Organization (CSIRO) both of Australia.
Sigma-Aldrich is making available sublicenses of the licensed patents as well as making available licensed Lentivirus-based shRNA Libraries for purchase through its catalog and web sites.
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For a commercial license to the DNA-directed RNA interference IP, please visit the Benitec Web site. |
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For information on research licenses, please contact:
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FLAG® Opportunities
Multiple Epitopes for Identification and Purification of Recombinant Proteins and
FLAG / ANTI-FLAG Trademarks |
Cleavable Multiple-FLAG (DYKDDDDK) epitope-tag expression and purification technology.
Use of FLAG / Anti-FLAG trademarks. |
| Discovery Tools |
Primary Screening
Secondary Screening (e.g. cell biological profiling or high content screening)
Target Discovery (proteomic or genomic based)
Target Validation (proteomic or genomic based)
Protein Expression
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Marketing Rights
Available/Desired |
Worldwide
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| Publications |
US Patent 6,379,903 (459 Kb PDF)
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For information on research licenses, please contact:
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HIS-Select® Opportunities
| HIS-Select Metal Chelate Composition &
iLAP™ (Integrated Lysis and Purification) Technologies |
| HIS-Select technology is a proprietary metal chelate with superior specificity over conventional nitrilotriacetic acid resins. iLAP is combined solid phase cell lysis and purification platform. Both technologies are also trademark registered. |
| Discovery Tools |
Protein Expression
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Marketing Rights
Available/Desired |
Worldwide
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| Publications |
Patents: US 7,033,520 (799 Kb PDF); US 6,623,655 (998 Kb PDF);
US 20060148090 (787 Kb PDF); US 20040092031 (773 Kb PDF);
US 20040259162 (2.5 Mb PDF)
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For information on research licenses, please contact:
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REDTaq® & REDAccuTaq® Opportunities
| REDTaq and REDAccuTaq are based on an invention using tracer reagents to enhance PCR and RT-PCR reaction-product analysis enabling simple direct gel loading for visualization. |
| Discovery Tools |
Genomics
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Marketing Rights
Available/Desired |
Worldwide
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| Publications |
Relevant patent and patent applications: US 6,942,964 (1.3 Mb PDF);
US20050148009 (1.2 Mb PDF); US20050148010 (1.2 Mb PDF);
US20050148011 (1.2 Mb PDF). REDTaq and REDAccuTaq are registered
trademarks of Sigma-Aldrich
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For information on research licenses, please contact:
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Whole Genome Amplification Opportunities
| Whole Genome Amplification Technology |
| Discovery Tools |
Pharmacogenetics/genomics
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Marketing Rights
Available/Desired |
Worldwide
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| Field of use restriction |
Research use and service providers
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| Publications |
US Patent Application No. 10/795,667 (7.2 Mb PDF)
International Application No. PCT/US204/00693 Titled "Amplification and
Analysis of Whole Genome and Whole Transcriptome Libraries Generated
by a DNA Polymerization Process"
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For information on research licenses, please contact:
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Whole Transcriptome Amplification Opportunities
| Whole Transcriptome Amplification Technology |
| Discovery Tools |
Pharmacogenetics/genomics
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Marketing Rights
Available/Desired |
Worldwide
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| Field of use restriction |
Research use and service providers
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| Publications |
US Patent Application No. 10/795,667 (7.2 Mb PDF)
International Application No. PCT/US204/00693 Titled "Amplification and
Analysis of Whole Genome and Whole Transcriptome Libraries Generated
by a DNA Polymerization Process"
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For information on research licenses, please contact:
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Chemistry Opportunities
Mono- and Diisopinocampheylhaloboranes as New Chiral Reducing Agents
US Patent 4772752 (406 Kb PDF)
Process for Producing Optically Active Alcohols
US Patent 4866181 (409 Kb PDF)
Process for Preparing Optically Active Haloalcohols
US Patent 4918246 (1.04 Mb PDF)
Novel Process for Producing Phenyl or Substituted Phenylalkylamine Pharmaceutical Agents and Novel Chiral Intermediates of High Enatiomeric Purity Useful Therein
US Patent 4950791 (552 Kb PDF)
Chemically and Optically Pure Diisopinocampheylhaloboranes
US Patent 5043479 (402 Kb PDF)
Borane-Sulfide Hydroboration Agents
US Patent 5567849 (465 Kb PDF)
Dioxane-Monochloroborane and Dioxane-Dichloroborane
US Patent 6008414 (386 Kb PDF)
Stabilized Borane-Tetrahydrofurane Complex
US Patent WO06020639A2 (1.81 Mb PDF)
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For more information, please contact:
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