SAFC Biosciences Introduces Liquid LONG®R3IGF-I |
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September 17, 2007 |
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Lenexa, KS - September 17, 2007 - SAFC Biosciences, a member of the Sigma-Aldrich Group (Nasdaq:SIAL), has announced the availability in liquid form of its LONG®R3IGF-I recombinant analog of human insulin-like growth factor-I.
LONG®R3IGF-I additive has been specifically engineered as a critical cGMP raw material for cell culture performance enhancement in either research or large scale culture systems. The liquid has a number of additional benefits to the lyophilized powder version, while convenience and specificity make it a superior alternative to insulin.
Both insulin and LONG®R3IGF-I bind to type IIGF receptors to stimulate cell growth in serum-free media - and crucially provide an animal component-free (ACF) additive meeting cGMP standards. Liquid LONG®R3IGF-I provides an easy-to-use ACF solution, which can be directly used in multiple cell culture applications without the need for reconstitution or thawing.
With equivalent performance to lyophilized LONG®R3IGF-I, the liquid version is a stable solution at 1 mg/mL in 100mM acetic acid. It is available in 5mL vial or 100 mL bottle quantities, stable at 4 - 8°C and can be used straight from refrigeration. Additionally, there are no differences in the manufacturing process for liquid as compared to the lyophilized powder version ensuring consistent products.
Commenting on the introduction, Rod Kelley, President of SAFC Biosciences, said: "LONG®R3IGF-I has successfully met the need for a secure supply of ACF additives to stimulate cell growth - and both the research and production communities will benefit from the convenience of the easy-to-use liquid option".
In its original form, LONG®R3IGF-I was re-launched in Spring 2006 and is used in at least eight FDA/EMEA-approved biopharmaceutical products. It is more biologically potent in vitro than insulin or native IGF-I and has been shown to significantly increase recombinant protein production.
SAFC Biosciences is the industry leader in cell culture science and service for global healthcare and one of four operating segments of SAFC - alongside SAFC Pharma, SAFC Supply Solutions and SAFC Hitech. With annual sales over US $500m., SAFC is a major player in the pharma and biopharma fine chemicals sectors, and one of the world's 10 largest fine chemical businesses.
About SAFC Biosciences:
SAFC Biosciences provides an integrated services package in mammalian cell culture media development and production, from pre-clinical and clinical development to commercialisation. Main product lines include serum-free media; serum-based products, growth factors and single use disposable bioprocessing systems.
Headquartered in Lenexa, Kansas USA, SAFC Biosciences has six production facilities in the US, Europe and Australia, and employs 600 people.
About SAFC: SAFC® is the custom manufacturing and services group within Sigma-Aldrich that
focuses on high-purity inorganics for high technology applications, cell culture products and services for biopharmaceutical manufacturing, biochemical production and the manufacturing of complex, multi-step organic synthesis of APIs and key intermediates. SAFC has manufacturing facilities around the world dedicated to providing manufacturing services for companies requiring a reliable partner to produce their custom manufactured materials. SAFC has four operating segments – SAFC Pharma™, SAFC Supply Solutions™, SAFC Biosciences™, and SAFC Hitech™ – and had annual sales of nearly $500 million in 2006. SAFC is one of the world's 10 largest fine chemicals businesses.
About Sigma-Aldrich: Sigma-Aldrich is a leading Life Science and High Technology company. Our biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. We have customers in life science companies, university and government institutions, hospitals and in industry. Over one million scientists and technologists use our products. Sigma-Aldrich operates in 36 countries and has 7,700 employees providing excellent service worldwide. We are committed to accelerating Customers' success through leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit our award-winning web site at sigma-aldrich.com.
Cautionary Statement: This release contains forward-looking statements relating to future performance, goals, strategic actions and initiatives and similar intentions and beliefs and other statements regarding the Companies' expectations, goals, beliefs, intentions and the like, which involve assumptions regarding the Companies' operations and conditions in the markets the Companies serve. The Companies do not undertake any obligation to update these forward-looking statements.
SAFC® is a registered trademark of Sigma-Aldrich Biotechnology L.P.
Forward Inquiries To:
Bruce Lehr
Director of Marketing
SAFC Biosciences
+ (913).227.6790 |
Media Inquiries:
Mr. Richard Kerns
Northern Exposure
+44.161.728.5880 |
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