Upstream Processing

Biopharmaceutical
 

Upstream processing of biopharmaceutical proteins utilizes two main tools: bioreactors and genetically engineered cells. Upstream processing requires high quality materials, especially of non-animal origin (NAO). SAFC provides these to ensure consistent bioreactor output at large scale. We can customize our products to meet your processing requirements. We also offer extensive expertise in batch, fed-batch, and perfusion culture bioreactor systems to maximize your upstream yields.

Capabilities
The largest powder media batches in the industry
Large-scale aseptic liquid (10,000 L) manufacturing and packaging (20 to 500 L)
Cell Culture media development and optimization services - especially NAO formulation
Custom cGLP media sample services
Analytical testing and spent medium analysis
Supply of a wide array of NAO media supplements

  Product line competencies:
Amino Acids
BEVS Production Reagents
Biological Buffers
Bioproduction Media
Cell culture
Non-animal origin components
   
  Operational competencies:
Analytical Testing Services
Animal / Non-animal Segregation
Aseptic Dispensing
Biopharmaceutical Services
cGMP Biopharmaceuticals
Fermentation
Large Scale Liquid Manufacturing
Large Scale Powder Manufacturing
Process Development Services