Biological
detergents are most commonly used to disrupt the bipolar lipid membrane of
cells in order to first free and then solubilize membrane-bound proteins. Some
detergents can also be used to solubilize recombinant protein, while others
find their usage in the stabilization, crystallization, or denaturation of
proteins.
Additional applications include the extraction of DNA and RNA, the
solubilization of specimens for diagnostic applications, the lysis of cells,
the preparation
of liposomes, the prevention of reagent and analyte precipitation from solution,
and the prevention of non-specific binding in immunoassays.
Specialties
Custom formulation
Custom manufacturing
Large scale batches
Advantages
Fully validated equipment
Lot-to-lot consistency and quality
Rigid cGMP specificatons
cGMP, low peroxide and non-animal source detergents available