Columns for Synthesizers

Proligo® Reagents
 
Product Breadth of Proligo Reagents
 Phosphoramidites :
Pharmadite®
DNA Phosphoramidites
RNA Phosphoramidites
2'O-Methyl RNA Phosphoramidites
 Fast Deprotection Chemistries :
DNA
RNA
 Supports :
Controlled Pore Glass (CPG)
Columns
 Solvents :
Liquid Reagents
Activator 42™
 Modifications :
Fluorescein Phosphoramidite
Biotin Phosphoramidite
Phosphate-ON Phosphoramidite
Non Standard Nucleosides
 Linkers :
Amino Linkers
ssH Linker
Product Breadth of Proligo Reagents


Since Merrifield first described solid phase synthesis, researchers have investigated numerous supports for the chemical synthesis of DNA. Controlled Pore Glass (CPG) has proven to be the most accepted standard, with features such as high surface area, efficient mass transfer and chemical inertness.

Because the pore density of CPG can be adjusted, the solid support can be tailored to the size of the synthetic oligonucleotide required. Bigger pore size is typically preferable in minimizing steric effects during the synthesis of long oligonucleotides, while smaller pore size fosters improved synthesis consistency.

Our process guarantees consistent production of CPGs to specifications designed for DNA synthesis.

All products are tested in our Quality Control labs for purity and identity prior to release. SAFC Proligo Reagent’s facility in Hamburg, Germany is ISO 9001 certified.
 On this Page
Cyclopeadic columns for ABI and Expedite synthesizer
DNA columns for Expedite synthesizers
Columns for ABI 3900 synthesizers
RNA columns for ABI synthesizers
RNA columns for Expedite synthesizers

Cyclopeadic columns for ABI and Expedite synthesizer

  • Filled with CPG 500Å and CPG 1000Å
  • Available in 50 nmol, 0,2 µmol and 1 µmol
  • No leakage (no crimping)
  • One column body
  • Color coded body, limits the wrong use of base in synthesis
Cyclopeadic columns for ABI and Expedite synthesizer
Compatible with ABI 392, 394, 3400 & Expedite 89 series Instruments
Product No. Description Unit
A341010-01 Column CPG 500Å dA(bz), 50 nmol, ABI/89 1 x 100
C341010-01 Column CPG 500Å dC(bz), 50 nmol, ABI/89 1 x 100
G341010-01 Column CPG 500Å dG(ib), 50 nmol, ABI/89 1 x 100
T341010-01 Column CPG 500Å dT, 50 nmol, ABI/89 1 x 100
A351010-01 Column CPG 500Å dA(bz), 0.2 μmol, ABI/89 1 x 100
C351010-01 Column CPG 500Å dC(bz), 0.2 μmol, ABI/89 1 x 100
G351010-01 Column CPG 500Å dG(ib), 0.2 μmol, ABI/89 1 x 100
T351010-01 Column CPG 500Å dT, 0.2 μmol, ABI/89 1 x 100
A361010-01 Column CPG 500Å dA(bz), 1 μmol, ABI/89 1 x 100
C361010-01 Column CPG 500Å dC(bz), 1 μmol, ABI/89 1 x 100
G361010-01 Column CPG 500Å dG(ib), 1 μmol, ABI/89 1 x 100
T361010-01 Column CPG 500Å dT, 1 μmol, ABI/89 1 x 100
A451010-01 Column CPG 1000Å dA(bz), 0.2 μmol, ABI/89 1 x 100
C451010-01 Column CPG 1000Å dC(bz), 0.2 μmol, ABI/89 1 x 100
G451010-01 Column CPG 1000Å dG(ib), 0.2 μmol, ABI/89 1 x 100
T451010-01 Column CPG 1000Å dT, 0.2 μmol, ABI/89 1 x 100
A461010-01 Column CPG 1000Å dA(bz), 1 μmol, ABI/89 1 x 100
C461010-01 Column CPG 1000Å dC(bz), 1 μmol, ABI/89 1 x 100
G461010-01 Column CPG 1000Å dG(ib), 1 μmol, ABI/89 1 x 100
T461010-01 Column CPG 1000Å dT, 1 μmol, ABI/89 1 x 100

DNA columns for Expedite synthesizers

  • Filled with CPG 500Å and CPG 1000Å
  • For Expedite 89er series synthesizers only
  • Crimped
  • Color coded label
DNA Columns
Compatible with Expedite™ Instruments
Product No. Description Unit
A311010-01 Column CPG 500Å dA(bz), 50 nmol 1 x 100
C311010-01 Column CPG 500Å dC(bz), 50 nmol 1 x 100
G311010-01 Column CPG 500Å dG(ib), 50 nmol 1 x 100
T311010-01 Column CPG 500Å dT, 50 nmol 1 x 100
A321010-01 Column CPG 500Å dA(bz), 0.2 μmol 1 x 100
C321010-01 Column CPG 500Å dC(bz), 0.2 μmol 1 x 100
G321010-01 Column CPG 500Å dG(ib), 0.2 μmol 1 x 100
T321010-01 Column CPG 500Å dT, 0.2 μmol 1 x 100
A331010-01 Column CPG 500Å dA(bz), 1 μmol 1 x 100
C331010-01 Column CPG 500Å dC(bz), 1 μmol 1 x 100
G331010-01 Column CPG 500Å dG(ib), 1 μmol 1 x 100
T331010-01 Column CPG 500Å dT, 1 μmol 1 x 100
A421010-01 Column CPG 1000Å dA(bz), 0.2 μmol 1 x 100
C421010-01 Column CPG 1000Å dC(bz), 0.2 μmol 1 x 100
G421010-01 Column CPG 1000Å dG(ib), 0.2 μmol 1 x 100
T421010-01 Column CPG 1000Å dT, 0.2 μmol 1 x 100
A431010-01 Column CPG 1000Å dA(bz), 1 μmol 1 x 100
C431010-01 Column CPG 1000Å dC(bz), 1 μmol 1 x 100
G431010-01 Column CPG 1000Å dG(ib), 1 μmol 1 x 100
T431010-01 Column CPG 1000Å dT, 1 μmol 1 x 100
Product No. Description Unit
A371001-01 Column CPG 500Å dA(bz), 15 μmol 1 x 1
C371001-01 Column CPG 500Å dC(bz), 15 μmol 1 x 1
G371001-01 Column CPG 500Å dG(ib), 15 μmol 1 x 1
T371001-01 Column CPG 500Å dT, 15 μmol 1 x 1
A471001-01 Column CPG 1000Å dA(bz), 15 μmol 1 x 1
C471001-01 Column CPG 1000Å dC(bz), 15 μmol 1 x 1
G471001-01 Column CPG 1000Å dG(ib), 15 μmol 1 x 1
T471001-01 Column CPG 1000Å dT, 15 μmol 1 x 1
Custom Products Bulk packaging up to multiple kg per container and customized packaging with alternative quantities of amidites are available upon request.
  CPG-products can be provided with higher loadings based on UHL-CPG (50-70 µmol/g or 90-110 µmol/g), please enquire.

Columns for ABI 3900 synthesizers

  • Filled with Polystyrene
  • For ABI 3900 synthesizers only
  • Available in 40 nmol, 0,2 µmol
  • Polystyrene 40 is comparable with CPG 1000Å
  • Color coded body, limits the wrong use of base in synthesis
DNA Columns
Compatible with ABI 3900 synthesizers
Product No. Description Unit
A911010-01 Column Polystyrene 40 dA(bz), 50 nmol, ABI 390 1 x 100
C911010-01 Column Polystyrene 40 dC(bz), 50 nmol, ABI 390 1 x 100
G915010-01 Column Polystyrene 40 dG(dmf), 50 nmol, ABI 300 1 x 100
T911010-01 Column Polystyrene 40 dT, 50 nmol, ABI 390 1 x 100
A921010-01 Column Polystyrene 40 dA(bz), 0.2 μmol, ABI 390 1 x 100
C921010-01 Column Polystyrene 40 dC(bz), 0.2 μmol, ABI 390 1 x 100
G925010-01 Column Polystyrene 40 dG(dmf), 0.2 μmol, ABI 390 1 x 100
T921010-01 Column Polystyrene 40 dT, 0.2 μmol, ABI 390 1 x 100

RNA columns for ABI synthesizers

  • Filled with CPG 500Å
  • For ABI 39X/3400 synthesizers only
  • Crimped
  • Color coded label
Fast Deprotection RNA Columns
Compatible with ABI Instruments
Product No. Description Unit
A662004-01 Column CPG 500Å rA(tac), 1 μmol 1 x 4
C662004-01 Column CPG 500Å rC(tac), 1 μmol 1 x 4
G662004-01 Column CPG 500Å rG(tac), 1 μmol 1 x 4
U661004-01 Column CPG 500Å rU, 1 μmol 1 x 4
2'0-Methyl RNA Columns
Compatible with ABI Instruments
Product No. Description Unit
A661104-01 Column CPG 500Å 2'O-Me-rA(bz), 1 μmol 1 x 4
C662104-01 Column CPG 500Å 2'O-Me-rC(tac), 1 μmol 1 x 4
G661104-01 Column CPG 500Å 2'O-Me-rG(ib), 1 μmol 1 x 4
U661104-01 Column CPG 500Å 2'O-Me-rU, 1 μmol 1 x 4

RNA columns for Expedite synthesizers

  • Filled with CPG 500Å and CPG 1000Å
  • For ABI 39X/3400 synthesizers only
  • Crimped
  • Color coded label
Fast Deprotection RNA Columns
Compatible with expedite instruments
Product No. Description Unit
A632004-01 Column CPG 500Å rA(tac), 1 μmol 1 x 4
C632004-01 Column CPG 500Å rC(tac), 1 μmol 1 x 4
G632004-01 Column CPG 500Å rG(tac), 1 μmol 1 x 4
U631004-01 Column CPG 500Å rU, 1 μmol 1 x 4
2'0-Methyl RNA Columns
Compatible with expedite instruments
Product No. Description Unit
A631104-01 Column CPG 500Å 2'O-Me-rA(bz), 1 μmol 1 x 4
C632104-01 Column CPG 500Å 2'O-Me-rC(tac), 1 μmol 1 x 4
G631104-01 Column CPG 500Å 2'O-Me-rG(ib), 1 μmol 1 x 4
U631104-01 Column CPG 500Å 2'O-Me-rU, 1 μmol 1 x 4

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