Since Merrifield first described solid phase synthesis, researchers have investigated numerous supports for the chemical synthesis of DNA. Controlled Pore Glass (CPG) has proven to be the most accepted standard, with features such as high surface area, efficient mass transfer and chemical inertness.
Because the pore density of CPG can be adjusted, the solid support can be tailored to the size of the synthetic oligonucleotide required. Bigger pore size is typically preferable in minimizing steric effects during the synthesis of long oligonucleotides, while smaller pore size fosters improved synthesis consistency.
Our process guarantees consistent production of CPGs to specifications designed for DNA synthesis.
All products are tested in our Quality Control labs for purity and identity prior to release. SAFC Proligo Reagent’s facility in Hamburg, Germany is ISO 9001 certified.
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- Filled with CPG 500Å and CPG 1000Å
- Available in 50 nmol, 0,2 µmol and 1 µmol
- No leakage (no crimping)
- One column body
- Color coded body, limits the wrong use of base in synthesis
| Cyclopeadic columns for ABI and Expedite synthesizer |
| Compatible with ABI 392, 394, 3400 & Expedite 89 series Instruments |
| Product No. |
Description |
Unit |
| A341010-01 |
Column CPG 500Å dA(bz), 50 nmol, ABI/89 |
1 x 100 |
| C341010-01 |
Column CPG 500Å dC(bz), 50 nmol, ABI/89 |
1 x 100 |
| G341010-01 |
Column CPG 500Å dG(ib), 50 nmol, ABI/89 |
1 x 100 |
| T341010-01 |
Column CPG 500Å dT, 50 nmol, ABI/89 |
1 x 100 |
| A351010-01 |
Column CPG 500Å dA(bz), 0.2 μmol, ABI/89 |
1 x 100 |
| C351010-01 |
Column CPG 500Å dC(bz), 0.2 μmol, ABI/89 |
1 x 100 |
| G351010-01 |
Column CPG 500Å dG(ib), 0.2 μmol, ABI/89 |
1 x 100 |
| T351010-01 |
Column CPG 500Å dT, 0.2 μmol, ABI/89 |
1 x 100 |
| A361010-01 |
Column CPG 500Å dA(bz), 1 μmol, ABI/89 |
1 x 100 |
| C361010-01 |
Column CPG 500Å dC(bz), 1 μmol, ABI/89 |
1 x 100 |
| G361010-01 |
Column CPG 500Å dG(ib), 1 μmol, ABI/89 |
1 x 100 |
| T361010-01 |
Column CPG 500Å dT, 1 μmol, ABI/89 |
1 x 100 |
| A451010-01 |
Column CPG 1000Å dA(bz), 0.2 μmol, ABI/89 |
1 x 100 |
| C451010-01 |
Column CPG 1000Å dC(bz), 0.2 μmol, ABI/89 |
1 x 100 |
| G451010-01 |
Column CPG 1000Å dG(ib), 0.2 μmol, ABI/89 |
1 x 100 |
| T451010-01 |
Column CPG 1000Å dT, 0.2 μmol, ABI/89 |
1 x 100 |
| A461010-01 |
Column CPG 1000Å dA(bz), 1 μmol, ABI/89 |
1 x 100 |
| C461010-01 |
Column CPG 1000Å dC(bz), 1 μmol, ABI/89 |
1 x 100 |
| G461010-01 |
Column CPG 1000Å dG(ib), 1 μmol, ABI/89 |
1 x 100 |
| T461010-01 |
Column CPG 1000Å dT, 1 μmol, ABI/89 |
1 x 100 |
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- Filled with CPG 500Å and CPG 1000Å
- For Expedite 89er series synthesizers only
- Crimped
- Color coded label
| DNA Columns |
| Compatible with Expedite™ Instruments |
| Product No. |
Description |
Unit |
| A311010-01 |
Column CPG 500Å dA(bz), 50 nmol |
1 x 100 |
| C311010-01 |
Column CPG 500Å dC(bz), 50 nmol |
1 x 100 |
| G311010-01 |
Column CPG 500Å dG(ib), 50 nmol |
1 x 100 |
| T311010-01 |
Column CPG 500Å dT, 50 nmol |
1 x 100 |
| A321010-01 |
Column CPG 500Å dA(bz), 0.2 μmol |
1 x 100 |
| C321010-01 |
Column CPG 500Å dC(bz), 0.2 μmol |
1 x 100 |
| G321010-01 |
Column CPG 500Å dG(ib), 0.2 μmol |
1 x 100 |
| T321010-01 |
Column CPG 500Å dT, 0.2 μmol |
1 x 100 |
| A331010-01 |
Column CPG 500Å dA(bz), 1 μmol |
1 x 100 |
| C331010-01 |
Column CPG 500Å dC(bz), 1 μmol |
1 x 100 |
| G331010-01 |
Column CPG 500Å dG(ib), 1 μmol |
1 x 100 |
| T331010-01 |
Column CPG 500Å dT, 1 μmol |
1 x 100 |
| A421010-01 |
Column CPG 1000Å dA(bz), 0.2 μmol |
1 x 100 |
| C421010-01 |
Column CPG 1000Å dC(bz), 0.2 μmol |
1 x 100 |
| G421010-01 |
Column CPG 1000Å dG(ib), 0.2 μmol |
1 x 100 |
| T421010-01 |
Column CPG 1000Å dT, 0.2 μmol |
1 x 100 |
| A431010-01 |
Column CPG 1000Å dA(bz), 1 μmol |
1 x 100 |
| C431010-01 |
Column CPG 1000Å dC(bz), 1 μmol |
1 x 100 |
| G431010-01 |
Column CPG 1000Å dG(ib), 1 μmol |
1 x 100 |
| T431010-01 |
Column CPG 1000Å dT, 1 μmol |
1 x 100 |
| Product No. |
Description |
Unit |
| A371001-01 |
Column CPG 500Å dA(bz), 15 μmol |
1 x 1 |
| C371001-01 |
Column CPG 500Å dC(bz), 15 μmol |
1 x 1 |
| G371001-01 |
Column CPG 500Å dG(ib), 15 μmol |
1 x 1 |
| T371001-01 |
Column CPG 500Å dT, 15 μmol |
1 x 1 |
| A471001-01 |
Column CPG 1000Å dA(bz), 15 μmol |
1 x 1 |
| C471001-01 |
Column CPG 1000Å dC(bz), 15 μmol |
1 x 1 |
| G471001-01 |
Column CPG 1000Å dG(ib), 15 μmol |
1 x 1 |
| T471001-01 |
Column CPG 1000Å dT, 15 μmol |
1 x 1 |
| Custom Products |
Bulk packaging up to multiple kg per container and customized packaging with alternative quantities of amidites are available upon request. |
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CPG-products can be provided with higher loadings based on
UHL-CPG (50-70 µmol/g or 90-110 µmol/g), please enquire. |
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- Filled with Polystyrene
- For ABI 3900 synthesizers only
- Available in 40 nmol, 0,2 µmol
- Polystyrene 40 is comparable with CPG 1000Å
- Color coded body, limits the wrong use of base in synthesis
| DNA Columns |
| Compatible with ABI 3900 synthesizers |
| Product No. |
Description |
Unit |
| A911010-01 |
Column Polystyrene 40 dA(bz), 50 nmol, ABI 390 |
1 x 100 |
| C911010-01 |
Column Polystyrene 40 dC(bz), 50 nmol, ABI 390 |
1 x 100 |
| G915010-01 |
Column Polystyrene 40 dG(dmf), 50 nmol, ABI 300 |
1 x 100 |
| T911010-01 |
Column Polystyrene 40 dT, 50 nmol, ABI 390 |
1 x 100 |
| A921010-01 |
Column Polystyrene 40 dA(bz), 0.2 μmol, ABI 390 |
1 x 100 |
| C921010-01 |
Column Polystyrene 40 dC(bz), 0.2 μmol, ABI 390 |
1 x 100 |
| G925010-01 |
Column Polystyrene 40 dG(dmf), 0.2 μmol, ABI 390 |
1 x 100 |
| T921010-01 |
Column Polystyrene 40 dT, 0.2 μmol, ABI 390 |
1 x 100 |
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- Filled with CPG 500Å
- For ABI 39X/3400 synthesizers only
- Crimped
- Color coded label
| Fast Deprotection RNA Columns |
| Compatible with ABI Instruments |
| Product No. |
Description |
Unit |
| A662004-01 |
Column CPG 500Å rA(tac), 1 μmol |
1 x 4 |
| C662004-01 |
Column CPG 500Å rC(tac), 1 μmol |
1 x 4 |
| G662004-01 |
Column CPG 500Å rG(tac), 1 μmol |
1 x 4 |
| U661004-01 |
Column CPG 500Å rU, 1 μmol |
1 x 4 |
| 2'0-Methyl RNA Columns |
| Compatible with ABI Instruments |
| Product No. |
Description |
Unit |
| A661104-01 |
Column CPG 500Å 2'O-Me-rA(bz), 1 μmol |
1 x 4 |
| C662104-01 |
Column CPG 500Å 2'O-Me-rC(tac), 1 μmol |
1 x 4 |
| G661104-01 |
Column CPG 500Å 2'O-Me-rG(ib), 1 μmol |
1 x 4 |
| U661104-01 |
Column CPG 500Å 2'O-Me-rU, 1 μmol |
1 x 4 |
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- Filled with CPG 500Å and CPG 1000Å
- For ABI 39X/3400 synthesizers only
- Crimped
- Color coded label
| Fast Deprotection RNA Columns |
| Compatible with expedite instruments |
| Product No. |
Description |
Unit |
| A632004-01 |
Column CPG 500Å rA(tac), 1 μmol |
1 x 4 |
| C632004-01 |
Column CPG 500Å rC(tac), 1 μmol |
1 x 4 |
| G632004-01 |
Column CPG 500Å rG(tac), 1 μmol |
1 x 4 |
| U631004-01 |
Column CPG 500Å rU, 1 μmol |
1 x 4 |
| 2'0-Methyl RNA Columns |
| Compatible with expedite instruments |
| Product No. |
Description |
Unit |
| A631104-01 |
Column CPG 500Å 2'O-Me-rA(bz), 1 μmol |
1 x 4 |
| C632104-01 |
Column CPG 500Å 2'O-Me-rC(tac), 1 μmol |
1 x 4 |
| G631104-01 |
Column CPG 500Å 2'O-Me-rG(ib), 1 μmol |
1 x 4 |
| U631104-01 |
Column CPG 500Å 2'O-Me-rU, 1 μmol |
1 x 4 |
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SAFC and SAFC Proligo Reagents are trademarks of Sigma-Aldrich Biotechnology, LP.
©2008 Sigma-Aldrich Biotechnology LP. All rights reserved. Reproduction forbidden without permission.
Other trademarks are the property of their respective owners. |
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