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RNA Phosphoramidites
	Proligo® Reagents

Product Breadth of Proligo Reagents

Phosphoramidites :
	Pharmadite®
	DNA Phosphoramidites
	RNA Phosphoramidites
	2'O-Methyl RNA Phosphoramidites
Fast Deprotection Chemistries :
	DNA
	RNA

Supports :
	Controlled Pore Glass (CPG)
	Columns
Solvents :
	Liquid Reagents
	Activator 42™

Modifications :
	Fluorescein Phosphoramidite
	Biotin Phosphoramidite
	Phosphate-ON Phosphoramidite
	Non Standard Nucleosides
Linkers :
	Amino Linkers
	ssH Linker

Product Breadth of Proligo Reagents

RNA Phosphoramidites with Fast Deprotection Chemistry



	Download Literature:
	•	User Instructions RNA Phosphoramidites (770k pdf)
	•	Standard RNA Phosphoramidites
	View Structure:
	•	rA(tac) Phosphoramidite
	•	rC(tac) Phosphoramidite
	•	rG(tac) Phosphoramidite
	•	rU Phosphoramidite

SAFC Proligo Reagents offers RNA phosphoramidite monomers with Fast Deprotection Chemistry (tert-butylphenoxyacetyl (TAC) group).

Advantages of synthesis with TAC-protected RNA phosphoramidites

Increased synthesis yield and reduced purification efforts

Dramatically reduced deprotection times

Minimized exposure to alkaline deprotection medium

Minimized chain degradation during deprotection

RNA Phosphoramidites
Compatible with Expedite™ and Polygen® Instruments
Product No.	Description	Unit
A211081-01	DMT-2′-O-TBDMS-rA(tac) amidite	1 x 0.5g
C213081-01	DMT-2′-O-TBDMS-rC(tac) amidite	1 x 0.5g
G211081-01	DMT-2′-O-TBDMS-rG(tac) amidite	1 x 0.5g
U211081-01	DMT-2′-O-TBDMS-rU amidite	1 x 0.5g
Compatible with ABI™ Instruments
Product No.	Description	Unit
A212031-01	DMT-2′-O-TBDMS-rA(tac) amidite	1 x 0.5g
A212061-01	DMT-2′-O-TBDMS-rA(tac) amidite	1 g
C212031-01	DMT-2′-O-TBDMS-rC(tac) amidite	1 x 0.5g
C212061-01	DMT-2′-O-TBDMS-rC(tac) amidite	1 g
G212031-01	DMT-2′-O-TBDMS-rG(tac) amidite	1 x 0.5g
G212061-01	DMT-2′-O-TBDMS-rG(tac) amidite	1 g
U211031-01	DMT-2′-O-TBDMS-rU amidite	1 x 0.5g
U211061-01	DMT-2′-O-TBDMS-rU amidite	1 g
Compatible with MerMade™ Instruments
Product No.	Description	Unit
A212028-06	DMT-2′-O-TBDMS-rA(tac) amidite	6 x 10g
C212028-06	DMT-2′-O-TBDMS-rC(tac) amidite	6 x 10g
G212028-06	DMT-2′-O-TBDMS-rG(tac) amidite	6 x 10g
U211028-06	DMT-2′-O-TBDMS-rU amidite	6 x 10g
Bulk Quantities
Product No.	Description	Unit
A212010-01	DMT-2′-O-TBDMS-rA(tac) amidite	1 x 10g
C212010-01	DMT-2′-O-TBDMS-rC(tac) amidite	1 x 10g
G212010-01	DMT-2′-O-TBDMS-rG(tac) amidite	1 x 10g
U211010-01	DMT-2′-O-TBDMS-rU amidite	1 x 10g
Fast Deprotection RNA CPG
Compatible with Expedite™ and Polygen® Instruments
Product No.	Description	Unit
A602001-01	CPG 500Å, rA(tac), 25-35 μmol/g	1 x 1g
C602001-01	CPG 500Å, rC(tac), 25-35 μmol/g	1 x 1g
G602001-01	CPG 500Å, rG(tac), 25-35 μmol/g	1 x 1g
U601001-01	CPG 500Å, rU, 25-35 μmol/g	1 x 1g
Fast Deprotection RNA Columns
Compatible with Expedite™ Instruments
Product No.	Description	Unit
A632004-01	Column CPG 500Å, rA(tac), 1 μmol	1 x 4
C632004-01	Column CPG 500Å, rC(tac), 1 μmol	1 x 4
G632004-01	Column CPG 500Å, rG(tac), 1 μmol	1 x 4
U631004-01	Column CPG 500Å, rU, 1 μmol	1 x 4
Compatible with ABI™ Instruments
Product No.	Description	Unit
A662004-01	Column CPG 500Å, rA(tac), 1 μmol	1 x 4
C662004-01	Column CPG 500Å, rC(tac), 1 μmol	1 x 4
G662004-01	Column CPG 500Å, rG(tac), 1 μmol	1 x 4
U661004-01	Column CPG 500Å, rU, 1 μmol	1 x 4
Custom Products	Bulk packaging up to multiple kg per container and customized packaging with alternative quantities of amidites are available upon request.

SAFC and SAFC Proligo Reagents are trademarks of Sigma-Aldrich Biotechnology, LP. ©2007 Sigma-Aldrich Biotechnology LP. All rights reserved. Reproduction forbidden without permission. Other trademarks are the property of their respective owners.
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