CYCLOBOND II is the gamma-cyclodextrin form of CYCLOBOND phases and consists of 8 glucopyranose units arranged in the same truncated cone shape. An excellent chiral selector for multi-ring structures, it is useful for isomeric compounds based on anthracene, chrysene and pyrene type ring structures. CYCLOBOND II offers good selectivity and stability, and is applicable to the polar organic mode of separation. Applications include steroids, porphorins, FMOC amino acids.