Preparative TLC is used for analytical separations of larger quantities of materials. Because sample mass loading capacity is proportional to the square root of the sorbent layer thickness, thicker layers are used (>250μm up to 1 mm). When a binder is required, the softer inorganic binders (like calcium sulphate) are used so the sample bands can be easily removed. The compounds to be separated are often applied as long streaks, developed and then recovered by scraping the adsorbent from the plate and eluting with a strong solvent.
Our glass plates for Preparative TLC are available coated with both unmodified and modified/bonded silica matrices, and are available with and without indicators.
