Reagents for Silylation

Silylation is the most widely used derivatization technique. Functional groups that present a problem with gas chromatogaphy detection - hydroxyl, carboxylic acid, amine, thiol, phosphate - can be derivatized by silylation reagents. Silylation involves replacement of the acidic hydrogen with an alkylsilyl group, for example, -SiMe3.
Silylation derivatives are generally less polar, more volatile and thermally more stable. The choice of a silylating reagent is based on its reactivity and selectivity towards the compound, the intended application, the stability of the derivative, and the abundance/nature of reaction byproducts.

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44795 N,O-Bis(tert-butyldimethylsilyl)acetamide for GC derivatization, ≥98.0% (GC)
89539 N,O-Bis(tert-butyldimethylsilyl)trifluoroacetamide for GC derivatization
14755 Bis(dimethylamino)dimethylsilane for GC derivatization, ≥95.0% (GC)
15269 N,O-Bis(trimethylsilyl)acetamide for GC derivatization, ≥98.5% (GC)
15241 N,O-Bis(trimethylsilyl)acetamide purum, ≥95.0% (GC)
15236 N,O-Bis(trimethylsilyl)carbamate ≥98.0% (T)
15235 N,N-Bis(trimethylsilyl)methylamine for GC derivatization, ≥97.0% (GC)
15222 N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, ≥99.0%
15238 N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for GC derivatization, contains 1% TMCS, 99% (excluding TMCS)
15209 N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane for GC derivatization, contains 10% TMCS, 98% (excluding TMCS)
15248 N,N′-Bis(trimethylsilyl)urea purum, ≥98.0% (N)
92337 Bromotrimethylsilane purum, ≥97.0% (AT)
15256   BSA+TMCS for GC derivatization, 93.0-97.0% (GC)
33151   BSA+TMCS+TMSI 3:2:3, pkg of 144 × 0.1 mL
33030   BSA+TMCS+TMSI 3:2:3, pkg of 20 × 1 mL
33084   BSTFA, Derivatization Grade for GC derivatization
33024   BSTFA, Derivatization Grade for GC derivatization
94380 tert-Butyl(chloro)diphenylsilane for GC derivatization, ≥98.0% (GC)
06735 tert-Butyldimethylsilyl chloride for GC derivatization, ≥99.0% (GC)
79262 tert-Butyldimethylsilyl methallylsulfinate for GC derivatization
00942 N-tert-Butyldimethylsilyl-N-methyltrifluoroacetamide with 1% tert-Butyldimethylchlorosilane for GC derivatization, ≥95.0% (GC)
56563 tert-Butyldimethylsilyl trifluoromethanesulfonate for GC derivatization, ≥98.0% (T)
76750 Chlorodimethyl(pentafluorophenyl)silane for GC derivatization, ≥95.0%
90383 Chlorotriethylsilane for GC derivatization, ≥97.0% (GC)
92090 Chlorotriisopropylsilane purum, ≥95.0% (GC)
33014   Chlorotrimethylsilane pkg of 100 mL
92360 Chlorotrimethylsilane puriss., ≥99.0% (GC)
89595 Chlorotrimethylsilane for GC derivatization, ≥99.0% (GC)
41663 1,3-Dimethyl-1,1,3,3-tetraphenyldisilazane ≥98.0% (NT)
41720 N,N-Dimethyltrimethylsilylamine purum, ≥95.0% (GC)
52619 Hexamethyldisilazane for GC derivatization, ≥99.0% (GC)
01565 Hexamethyldisiloxane for GC derivatization, ≥98% (GC)
33046   HMDS+TMCS 3:1, pkg of 20 × 1 mL
33038   HMDS+TMCS+Pyridine, 3:1:9 (Sylon HTP) pkg of 20 × 1 mL
33039   HMDS+TMCS+Pyridine, 3:1:9 (Sylon HTP) pkg of 25 mL
69480 N-Methyl-N-trimethylsilylacetamide for GC derivatization, ≥97.0% (GC)
69484 N-Methyl-N-trimethylsilylheptafluorobutyramide for GC derivatization, ≥90% (GC)
68768 N-Methyl-N-(trimethyl-d9-silyl)trifluoroacetamide for GC derivatization, ≥94.0% (GC)
69479 N-Methyl-N-(trimethylsilyl)trifluoroacetamide for GC derivatization, ≥98.5%
50992   N-Methyl-N-trimethylsilyltrifluoroacetamide activated I for GC derivatization, activated with ethanethiol and ammonium iodide
12245   N-Methyl-N-trimethylsilyltrifluoroacetamide activated I for GC, activated with ethanethiol and ammonium iodide
44156   N-Methyl-N-trimethylsilyltrifluoroacetamide activated II for GC derivatization, activated with 2-(Trimethylsilyl)ethanethiol
12124 N-Methyl-N-trimethylsilyltrifluoroacetamide activated III for GC derivatization, activated with imidazole
69478 N-Methyl-N-(trimethylsilyl)trifluoroacetamide with 1% trimethylchlorosilane for GC derivatization
85434 Silylating mixture I according to Sweeley for GC derivatization, ampule
85431 Silylating mixture I according to Sweeley for GC derivatization
85435   Silylating mixture II according to Horning for GC derivatization
85432   Silylating mixture II according to Horning for GC derivatization
85433 Silylating mixture III for GC derivatization
505846   Silylation Sampler Kit
43340 1,1,3,3-Tetramethyl-1,3-diphenyldisilazane for GC derivatization, n/D
91566 N-(Trimethylsilyl)acetamide for GC derivatization, ≥98.0% (GC)
394874 1-(Trimethylsilyl)imidazole for GC derivatization
92718 1-(Trimethylsilyl)imidazole - Pyridine mixture for GC derivatization
79271 Trimethylsilyl methallylsulfinate for GC derivatization, ≥90.0% (GC)