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Solid Phase Microextraction (SPME)

Solid phase microextraction is a fast, solventless alternative to conventional sample extraction techniques. In SPME, analytes establish equilibria among the sample matrix, the headspace above the sample, and a polymer-coated fused fiber, then are desorbed from the fiber to a chromatography column. Because analytes are concentrated on the fiber, and are rapidly delivered to the column, minimum detection limits are improved and resolution is maintained.
SPME is compatible with analyte separation/detection by gas chromatography or HPLC, and provides linear results for wide concentrations of analytes.
Get an Introduction to SPME through our instructional SPME video series.