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Primary Reference Standards for the Analysis of Herbal Medicinal Products
In collaboration with HWI ANALYTIK GmbH, a company with almost 20 years of experience in the analysis of pharmaceutical products, Sigma-Aldrich provides a new class of primary reference standards for the use in quality control, in-process control and stability testing of herbal medicinal products.
These standards are produced and qualified by HWI ANALYTIK, and are exclusively distributed by Sigma-Aldrich. The novel certification concept of these reference standards is based on the quantitative NMR technique (qNMR) for content assignment. The application of qNMR, a relative primary method of measurement, is advantageous compared to the usual combination of two chromatographic methods, Karl Fischer titration and residual solvent determination due to higher reliability of the certified content value. The analytical report delivered with these products contains two identity proofs, the content by qNMR and the chromatographic purity.
Comprehensive documentation on further parameters, detailed method descriptions and validation data can be ordered directly from HWI ANALYTIK.
| Product No. |
Description |
Add to Cart |
| 00130590-100mg |
trans-Anethol |
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| 00720585-10mg |
Apigenin-7-glucoside |
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| 00630590-25mg |
Bisabolol oxide A, primary reference standard |
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| 00500590-10mg |
Chlorogenic acid, primary reference standard |
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| 01260595-25mg |
Coumarin, primary reference standard |
|
| 00020590-100mg |
Eucalyptol (1,8-Cineol) |
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| 00380590-100mg |
(+)-Fenchon |
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| 00770590-10mg |
Ginkgolide A, primary reference standard |
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| 02580185-10mg |
* Ginkgolic acid C15:1, primary reference standard |
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| 01390590-10mg |
Ginkgolic acid C17:1, primary reference standard |
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| 00170580-10mg |
Ginsenoside Rb1, primary reference standard |
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| 00370580-10mg |
Ginsenoside Rg1, primary reference standard |
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| 00420580-10mg |
Harpagoside, primary reference standard |
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| 01090595-10mg |
Hulupinic acid, primary reference standard |
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| 00190180-10mg |
* Hypericin, primary reference standard |
|
| 00180585-10mg |
Hyperoside, primary reference standard |
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| 00140585-10mg |
Isoquercitrin, primary reference standard |
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| 00580590-100mg |
(-)-Menthol |
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| 00040590-100mg |
alpha-Pinene |
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| 00200595-50mg |
Quercetin dihydrate, primary reference standard |
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| 00740580-10mg |
Quercitrin, primary reference standard |
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| 00390580-10mg |
Rosmarinic acid, primary reference standard |
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| 00300590-50mg |
Rutin trihydrate, primary reference standard |
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| 01870575-10mg |
Sennoside A, primary reference standard |
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| 00530580-10mg |
Sennoside B, primary reference standard |
|
| 02000585-10mg |
Silybin, primary reference standard |
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| 00670590-100mg |
Thymol |
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| 02010595-10mg |
Valerenic acid, primary reference standard |
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| 00820580-10mg |
Verbascoside |
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| 00660585-10mg |
Vitexin-2"-O-rhamnoside, primary reference standard |
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| 01130595-10mg |
Xanthohumol, primary reference standard |
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| Back to Top |
* for Ginkgolic acid C15:1 and Hypericin, the content determination by qNMR was not applicable due to overlapping signals. For these two products, the content has been assigned by the usual mode combining two chromatographic methods, water content by Karl Fischer and determination of residual solvents and of inorganic compounds.
A comprehensive list of analytical standards and reference materials for the analysis of herbal medicinal products can be found here. You can browse our products alphabetically, by substance class or by plant genus.
Additional Literature:
Analytix 01/2010 (PDF, 134 KB) Product Leaflet quantitative NMR (PDF, 85 KB)
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