CHIRALDEX DM

Astec CHIRALDEX B-DM and G-DM capillary GC columns incorporate a phase consisting of a 2,3-di-O-methyl-6-t-butyl silyl derivative of either β- or γ-cyclodextrin. These phases exhibit broad chiral selectivity, resolving aliphatic, olefenic, and aromatic enantiomers. They combine the selectivities of the PM and PH phases.

Features

• Broad chiral selectivity
• Combine selectivity of the PM and PH phases
• Short retention, high resolution
• B-DM broadly applicable
• Resolve aliphatic, olefenic and aromatic enantiomers

Mechanism Observations

• Size selectivity present but not dominant as in the DA phases
• Fewer structural requirements
• Characteristic temperature selectivity

Size Selectivity

Size selectivity is evident, therefore, the inclusion mechanism is playing a role in the separation mechanism but does not dominate as it does with the DA phases. The B-DM phase covers a very broad range of molecular sizes and, therefore, has the greatest applicability.

Specific Classes of Compounds Separated

Use this table as a reference to help determine the proper column based on the analyte(s) of interest.