|
|
Gas Chromatography
CHIRALDEX PH
|
|
|
Astec Products | Technical Resources | Chiral Services
Ordering Information: A-PH | B-PH
Astec CHIRALDEX A-PH and B-PH capillary GC columns incorporate a phase consisting of a (S)-2-hydroxy propyl methyl ether derivative of either α- or β-cyclodextrin. These phases separate a wide variety of enantiomers, resolving aliphatic, olefinic, and aromatic enantiomers. They are good general purpose chiral columns.
| Type / Name |
Derivative |
α-Phase |
β-Phase |
Max. Temp.(°C)
Isothermal |
Max. Temp.(°C)
Programmed |
| PH / Hydroxypropyl |
(S)-2-hydroxy propyl methyl ether |
A-PH |
B-PH |
200 |
220 |
Features
- Patented chiral stationary phases
- Hydrophilic surface
- Separate a wide variety of enantiomers
- Resolve aliphatic, olefinic, and aromatic enantiomers
- Good general purpose chiral columns
Mechanism Observations
- Reduced influence of inclusion complexing
- Less size selectivity than the DA phases
- Characteristic temperature selectivity on a given column for a given class of compounds
- Fewer functional requirements for analyte than LC
Size Selectivity
For the PH phases a minimal effect is seen based on size selectivity.
Specific Classes of Compounds Separated
Use this table as a reference to help determine the proper column based on the analyte(s) of interest.
| Type |
Compound Class |
| A-PH |
Small linear and saturated amines, alcohols, esters, and epoxides. |
| B-PH |
Most structural types of compounds, including linear and cyclic amines and alcohols, lactones, amino alcohols, sugars, bicyclics, epoxides, haloalkanes, aromatic and cyclic hydrocarbons, and more. Very useful for hydrocarbons. |
|
|
