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Analytical / Chromatography > Gas Chromatography > Capillary GC Columns > Astec CHIRALDEX > CHIRALDEX PH
Gas Chromatography

CHIRALDEX PH

Astec Products | Technical Resources  | Chiral Services
Ordering Information: A-PH | B-PH

Astec CHIRALDEX A-PH and B-PH capillary GC columns incorporate a phase consisting of a (S)-2-hydroxy propyl methyl ether derivative of either α- or β-cyclodextrin. These phases separate a wide variety of enantiomers, resolving aliphatic, olefinic, and aromatic enantiomers. They are good general purpose chiral columns.


Type / Name Derivative α-Phase β-Phase Max. Temp.(°C)
Isothermal
Max. Temp.(°C)
Programmed
PH / Hydroxypropyl (S)-2-hydroxy propyl methyl ether A-PH B-PH 200 220

Features

  • Chiral stationary phases for GC
  • Hydrophilic surface
  • Separate a wide variety of enantiomers
  • Resolve aliphatic, olefinic, and aromatic enantiomers
  • Good general purpose chiral columns

Mechanism Observations

  • Reduced influence of inclusion complexing
  • Less size selectivity than the DA phases
  • Characteristic temperature selectivity on a given column for a given class of compounds
  • Fewer functional requirements for analyte than LC

Size Selectivity

For the PH phases a minimal effect is seen based on size selectivity.


Specific Classes of Compounds Separated

Use this table as a reference to help determine the proper column based on the analyte(s) of interest.

Type Compound Class
A-PH Small linear and saturated amines, alcohols, esters, and epoxides.
B-PH Most structural types of compounds, including linear and cyclic amines and alcohols, lactones, amino alcohols, sugars, bicyclics, epoxides, haloalkanes, aromatic and cyclic hydrocarbons, and more. Very useful for hydrocarbons.
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