HPLC and UHPLC Columns

Supelco’s HPLC & UHPLC columns meet today’s challenging needs of Fast HPLC, LC-MS, biopolymer separation, high pH conditions, as well as traditional pharmacopeia and agency methods within pharmaceutical, environmental, and food industries. Fused-Core®, polymeric, monodisperse silica, ultra-pure silica, and zirconia are some of the particle platforms that make up the Supelco HPLC product line.

Supelco has a tradition of providing innovative HPLC Columns. While Supelcosil and Discovery are trusted brands with a proven track record, Titan™ delivers leading edge UHPLC performance at an affordable cost, and Ascentis® Express and BIOshell™ (based on Fused-Core technology) have the capability to turn any HPLC system into a Fast HPLC workhorse. Furthermore, Astec chiral chromatography columns are the solution for chiral LC-MS. Supelco/Sigma-Aldrich also supplies leading brand HPLC columns, including Kromasil, TSKgel, Hamilton, LiChrospher, more.

If you require a custom HPLC column, please contact Supelco_Quotes@sial.com or fill out the custom HPLC column request form to obtain a quote.

apHera™ - High pH
View on-demand HPLC webinars

Recent Webcast - Efficient Separation in UHPLC Using 2.0 µm Fused-Core Columns;registration required.

Ascentis (broad range of selectivities for easy method development)
Ascentis® Express (for UHPLC, Fast HPLC & High Resolution applications)
 Ascentis Express Columns with 2.0 µm particles for UHPLC
BIOshell (for separation of biomolecules)
Chiral (includes Astec lines of LC-MS compatible chiral columns)
Chromolith® HPLC Columns (Low backpressure; Long lifetime; available in micro format)
Discovery®  (large pore columns for peptides & protein applications)
ES Industries (Green Sep™ and ChromegaChiral™)
Kromasil® (premium silica for HPLC, SMB or SFC)
Other Column Brands (Hamilton, LiChrosorb, LiChrospher, Nucleosil, Spherisorb, alphaBond)
Purospher® STAR (100% aqueous phase compatibility; pH stability 1.5 – 10.5; Column/batch reproducibility)
Sepax® Technologies (ultra-efficient UHPLC columns for biopolymer separations)
SUPELCOGEL™ (for sugars, organic acids and alcohols)
SUPELCOSIL™ (traditional family of Supelco columns referenced in literature)
Titan™ UHPLC Columns — Excellent Performance; Great Value
TSKgel®  (leading Gel Filtration chromatography columns)

Browse Columns by Phase
Browse HPLC and FPLC columns for biopolymer separations
Browse online HPLC applications

Trademarks
apHera, Ascentis, Astec, BIOshell, Discovery, SUPELCOSIL, and Titan are trademarks of Sigma-Aldrich Co. LLC
Sepax is a trademark of Sepax Technologies
TSKgel is a trademark of Tosoh Corporation
Fused-Core is a trademark of Advanced Materials Technology, Inc.
Kromasil is a trademark of EKA Chemicals AB