Titan™ UHPLC Columns

Titan delivers leading UHPLC column performance, at half the cost

Titan UHPLC columns, based on 1.9 µm totally porous monodisperse silica, outperform other UHPLC columns. These UHPLC columns provide the performance scientists expect (typically > 250,000 N/m), but at a greatly reduced cost.
With the narrowest particle size distribution of all available sub-2 µm porous particles, Titan columns are the outcome of the highly efficient patent pending Ecoporous™ silica manufacturing process that delivers high-performance silica at a low cost.


  • Excellent Performance
  • Extremely Narrow Particle Size Distribution
  • Great Value

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Technical Resources:

Titan C18, 1.9 µm - ordering information
End-capped, stable, reversed-phase UHPLC column packing that performs well for basic, acidic, or neutral compounds.

Figure 1. Titan C18 Performance Comparison Using Different Column I.D.s
Conditions
mobile phase: 60% acetonitrile
temp.: 35 °C
det.: 254 nm

1. Uracil
2. Diazepam
3. Toluene
4. Naphthalene
5. Biphenyl

Figure 2. Titan C18 Performance Comparison Vs. Competitor UHPLC Columns
Conditions
column: 5 cm x 3.0 mm I.D.
mobile phase: 60% acetonitrile
flow rate: 0.9 mL/min
temp.: 35 °C
det.: 254 nm

1. Uracil
2. Diazepam
3. Toluene
4. Naphthalene
5. Biphenyl


Advantages of Using Monodisperse Particles in HPLC
The Titan particle is based on spherical, fully porous silica, with an ultra-narrow particle size distribution for optimum efficiency. Research findings[1] support observations that porous-layer particles with very narrow particle size distribution demonstrate superior efficiency and kinetic performance. Uniform Titan particles are packed into rugged column beds that are stable over a range of UHPLC flow and pressure conditions. Excellent batch reproducibility and robustness is also noted.

Figure 3. Comparison of Particle Size Distribution for Different Sub-2 µm Porous Particles



References:
1. D. Cabooter, A. Fanigliulo, G. Bellazzi, B. Allieri, A. Rottigni, G. Desmet, J. of Chromatography A, 1217 (2010) 7074–7081

Trademarks:
Titan and Ecoporous are trademarks of Sigma-Aldrich Co. LLC