3M Empore™ Products

Improving Sample Prep Performance through SPE Disk Technology

Empore SPE membrane technology comprises of SPE particles tightly enmeshed within a network of inert PTFE fibrils. The SPE membrane fabrication process results in a highly dense and uniform extraction medium that offers distinct advantages over traditional sorbent or packed-bed SPE products. Empore SPE technology provides a denser, more uniform extraction bed than traditional packed-bed products allowing for smaller bed weights, shorter analyte to pore diffusion paths, and more efficient extractions.

(Empore is a registered trademark of 3M Company)

Features and Benefits
Comparison of Solvent Use
Empore Product Range
Empore vs. Supelco Product Cross Reference
Ordering Information
Technical Resources

Features and Benefits

Key Features:

Comprised of 90% SPE Particle : 10% PTFE, by weight
Uses 47 µm SPE particles for improved flow characteristics
Optimized for difficult sample matrices (e.g., biological fluids)

Save Time & Money with Empore SPE:

Reduced SPE Bed Mass = Reduced SPE Solvent and Elution Volumes
Minimizes SPE eluate evaporation time
Potentially allows for direct injection of the SPE eluate
Dense & Uniform Extraction Medium = No SPE Channeling and Voiding
Efficient mass-transfer kinetics allow for faster flow rates
Eliminate SPE fines improving column and instrument life

Microscopic View of Empore SPE Disks

Microscopic view of Empore SPE Disks

Comparison of Solvent Volume Requirements for Traditional SPE Cartridges vs. Empore Cartridges

Typical Volume Examples
Cartridge	Bed Volume of Sorbent	Condition Volume	After Elution Step
Traditional cartridge 500mg/6 mL	600 µL	2400-3000 µL	1200-1800 µL
Traditional cartridge 100mg/1 mL	120 µL	480-600 µL	240-360 µL
Empore cartridge 7mm/3 mL (12 mg)	50 µL	200-250 µL	100-150 µL

Visual Comparison
Cartridge	Before Loading Sample	After Load/Wash Step	After Elution Step
Traditional 100 mg/1 mL Packed Bed SPE Cartridge

Empore 4 mm/1 mL SPE Disk Cartridge

Empore SPE Product Range


SPE Cartridges for General Use	96-well plates for Pharmaceutical Bioanalysis	Extraction Disks for Environmental Analysis

Our Empore Technical Library comprises of dozens of helpful resources, application examples, and an 80+ page application bibliography to facilitate efficient method development and troubleshooting.

your favorite gene search

Service & Support

Ordering

Corporate

©2011 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA, SAFC, SIGMA-ALDRICH, ALDRICH, and SUPELCO are trademarks of Sigma-Aldrich Co. LLC, registered in the US and other countries. FLUKA is a trademark of Sigma-Aldrich GmbH, registered in the US and other countries. Sigma brand products are sold through Sigma-Aldrich, Inc. Purchaser must determine the suitability of the product(s) for their particular use. Additional terms and conditions may apply. Site Use Terms | Privacy