SPE - 3M Empore™ Products

3M Empore™ SPE Cartridges

Empore SPE™ cartridges are packed with a PTFE membrane enmeshed with SPE particles. Layered above the SPE membrane is a polypropylene pre-filter that prevents particulates from reaching the underlying membrane. The dense particle packing and uniform distribution within the Empore membane offer outstanding extraction efficiency and reproducibility.


Ordering Information

Features & Benefits:
  • Reduced sample and elution volumes
  • Reduced time for eluate evaporation
  • Increased sampling throughput
  • No channeling effects
  • High and reproducible recoveries

1 (coarse density), 2 (medium density), 3 (fine density, made up of 5 individual layers), 4 (porous PP support)

Solvent Volume Guidelines for Empore SPE Cartridges
    Empore Catridge Sizes
Step Solvent 4 mm/1 mL 7 mm/3 mL 10 mm/6 mL
Condition Methanol
Water
150 µL
300 µL
250 µL
500 µL
500 µL
1000 µL
Load Sample
Buffer/IS
250 µL
250 µL
1000 µL
1000 µL
2000 µL
2000 µL
Wash Water
Organic/Aqueous
300 µL
300 µL
500 µL
500 µL
1000 µL
1000 µL
Elute Organic 100-150 µL 200-300 µL 600-800 µL
Notes: It is recommended to optimize the volume of elution solvent to ensure that the minimum volume is used that will elute the anlayte reproducibly from the sorbent phase. Due to the disruption of ionic interactions, which can be stronger than reversed-phase interactions, slightly more elution solvent volume may be required for mixed phase disks than for a reversed-phase sorbent.

Our Empore Technical Library comprises of dozens of helpful resources, application examples, and an 80+ page application bibliography to facilitate efficient method development and troubleshooting.