Solid Phase Extraction

Learning Center

Applications by Industry

Environmental
Food / Agriculture
Pharmaceutical / Biotechnology
Natural Products

Category / Title Type Size (kb) No. Pages I.D.
Environmental  
Dioxin & PCB Analysis Brochure 2,054 16 JXB
The Class-Selective Extraction and Analysis of β-Receptor Agonist and Antagonists using Molecularly Imprinted Polymer SPE (TheReporter 25.4) Article 218 3 T207004
The Extraction of Glycols From Water Using ENVI-Carb™ Plus Solid Phase Extraction Cartridges Presentation 280 25 T410135
Analysis of PCBs in Transformer Oil with a Sulfoxide Bonded SPE Phase and GC-MS Presentation 395 22 T408040
Extract Nonvolatile Pesticides from Drinking Water, Using a Graphitized Carbon Adsorbent App Note 027 130  T394027
Cleanup of Hazardous Waste Site Samples by Solid Phase Extraction App Note 028 131  T394028
Use Solid Phase Extraction to Isolate Phenols from Aqueous Samples App Note 032 127  T394032
Extract Polynuclear Aromatic Hydrocarbons from Water, Using Solid Phase Extraction Disks App Note 054 168  T394054
Extraction of Phthalates and Adipates from Water, Using Solid Phase Extraction Disks App Note 055 220  T394055
Extraction of Organic Compounds from Water, Using ENVI-18 DSK Solid Phase Extraction Disks App Note 059 224  T394059
Extraction of Paraquat and Diquat from Water, Using ENVI-8 DSK Solid Phase Extraction Disks App Note 060 174  T394060
Low Background Solid Phase Extraction and Capillary GC Analysis of Chlorinated Pesticides App Note 064 129  T395064
ENVI-18 SPE Tube Ensures Low Background for Monitoring Organic Compounds in Drinking Water by EPA Method 525 App Note 065 130  T395065
Solid Phase Extraction of PCBs from Transformer Oil and Waste Oil, and Analysis by Capillary GC  App Note 067 131  T395067
Solid Phase Extraction/HPLC Analysis of Acidic Herbicides in Drinking Water App Note 100 127  T396100
Single Solid Phase Extraction Procedure Yields Base/Neutral and Acidic Fractions, for HPLC Analysis App Note 105 133  T396105
Solid Phase Extraction Provides Interference-Free Samples for Analyzing Triazine Herbicides App Note 127 136  T397127
Food / Agriculture  
Solid Phase Extraction of Pesticides from Fruits and Vegetables, for Analysis by GC or HPLC Bulletin 900 135 T196900
Extraction of Nitroimidazoles from Milk and Egg Samples using SupelMIP SPE Nitroimidazoles and LC-MS-MS Tech Report 408  T409097
The Extraction and Analysis of Melamine in Milk-Based Products using Discovery DSC-SCX SPE and Ascentis Express HILIC LC-MS/MS Tech Report 370  T408188
Discovery Ag-Ion SPE for FAME Fractionation and cis/trans Separation Tech Report 655 8 T406062
Extraction of Pesticides from Agricultural Products Using Multi-Layer ENVI-Carb-II/PSA SPE Tubes Tech Report 294 8 T405060
NEW Custom “Dispersive” SPE Products for Pesticide and Acrylamide Analysis (TheReporter 23.4) Article 383 2 T205004
Extraction and Analyses of Agricultural Pesticides from Oranges Using the "QuEChERS" Method (TheReporter 24.3) Article 381 3 T206003
Determination of Acrylamide in Fried Potato Chips by Discovery DSC-MCAX, DSC-18 SPE and Discovery HS F5 LC-MS (TheReporter 22.5) Article 1,284 2 T204005
Fractionation of cis/trans FAMEs using Discovery Ag-Ion SPE (TheReporter 24.2) Article 248 2 T206002
The Selective Extraction of Chloramphenicol using Molecular Imprinted Polymer (MIP) SPE (TheReporter 25.1) Article 482 3 T207001
Acrylamide in Food: Kits, columns and tubes for sensitive GC-MS and LC-MS analyses and solid phase extraction (Analytix, Issue 2 - 2005) Article 97 3 n/a
Method for Analysis of Organophosphorous Pesticides in Produce using Acetonitrile Extraction, Dual-Layer Carbon-Aminopropylsilica Cleanup and GC-NPD Detection Presentation 527 20 T410102H
Detection of Low Level of Chloramphenicol in Milk & Honey with MIP SPE & LC-MS-MS Presentation 140 19 T407125
Fractionation of cis & trans Fatty Acid Isomers for Food Sample Analysis with Hexane/Acetone on Silver SPE Material Presentation 504 17 T406099
Application of Cis & Trans Fatty Acid Isomers from Process Cheeses Using Silver-Ion SPE Fractionation Presentation 318 15 T406101
Fractionation of cis & trans Fatty Acid Isomers for Food Sample Analysis on Silver SPE Material Presentation 680 19 T407018
The Extraction & Analysis of Multi-Residue Pesticides in Oranges Using Dispersive SPE & GC-MS Presentation 196 20 T406100
Analysis of Multi-Pesticide Residues in Vegetables, Food, and Fruits by SPE/GC-MS Presentation 304 21 T405020
Rapidly Analyze Sodium in Foods, Using Solid Phase Extraction and Cation-Exchange HPLC App Note 14 212 T394014
Pharmaceutical / Biotechnology  
Tobacco-Specific Nitrosamines: Efficient Extraction of Toxic Compounds from Complex Matrices using Molecularly Imprinted Polymers Tech Report 588 22 T407117
Simple, Fast and Class Selective Extraction of Amphetamine and Related Drugs from Urine using Molecularly Imprinted Polymer (MIP) SPE and LC/MS/MS Tech Report 505 6 T407148
Reversed-Phase LC/MS Analysis of Three Basic Pharmaceutical Compounds From Serum Using Discovery DSC-18 SPE-96 Plates and Discovery HS C18, 3µm Tech Report 71 4 T401203
Maximizing Selective/Sample Clean Up Using Discovery DSC-MCAX (Mixed-Mode Cation Exchange) SPE Tech Report 45 1 T404100
The Importance of Ion Exchange Capacity in Mixed-Mode SPE Tech Report 58 1 T404101
Reversed-Phase Selectivity of Discovery DSC-MCAX (Mixed-Mode Cation Exchange) SPE Tech Report 34 1 T404102
Fractionate Basic Analytes from Neutral and Acidic Compounds with Discovery DSC-MCAX SPE Tech Report 40 1 T404103
The Class-Selective Extraction and Analysis of β-Receptor Agonist and Antagonists using Molecularly Imprinted Polymer SPE (TheReporter 25.4) Article 218 3 T207004
SPE Tubes: A Classic Alternative to 96-Well Plates (sulfa drugs from serum) (Reporter 18.2) Article 123 2 T200012
Achieving Optimal Selectivity/Sample Clean Up Using Discovery DSC-MCAX (Mixed Cation) SPE (Reporter - 22.2) Article 1,239 2 T204003
The Importance of Ion-Exchange Capacity in Mixed-Mode SPE (TheReporter 3.1) Article 320 2 T204001
A Case Study in Method Development for the Extraction and Analysis of Lasix™ (Furosemide) from Horse Serum (Reporter 21.6) Article 614 3 T203016
LRA: Lipid Removal Agent (Analytix, Issue 5 - 2006) Article 42 2 T406053
The Determination of Hydrocortisone from Topical Cream Using Discovery DSC-Si SPE and Reversed-Phase HPLC-UV
(Online Reporter 21.8)
Article n/a n/a n/a
Extraction of the Beta-Agonist Clenbuterol from Urine Using Clenbuterol SupelMIP (European Reporter, Vol. 25) Article 136 3 n/a
Molecular Imprinted Polymer SPE Increases Sensitivity for the Extraction and Analysis of Clenbuterol from Urine (Reporter 25.2) Article 304 3 T207002
High Recovery Method of HybridSPE®-Phospholipid for Cleanup of Biological Samples Prior to LC-MS Analysis Presentation 465 22 T411056H
Detection of Clenbuterol at sub-ppb Levels Using Molecularly Imprinted Polymer SPE Methods for Sample Preparation Presentation 272 22 T407146
Comparison of SPE Methods for Reduction of Matrix Induced Ion-Suppression of Clenbuterol by Linear Ion Trap Presentation 192 20 T407089
Discovery Pharmaceutical Applications - Acetaminophen and Caffeine from Serum App Note 68 1 T499127
Discovery Pharmaceutical Applications - Antibiotics (Cephalosporins) from Serum App Note 69 1 T499127
Discovery Pharmaceutical Applications - Antibiotics (Sulfa Drugs) from Serum App Note 58 1 T499127
Discovery Pharmaceutical Applications - Anticonvulsant Compounds from Serum App Note 57 1 T499127
Discovery Pharmaceutical Applications - Anticonvulsants/Anxiolytics from Serum App Note 57 1 T499127
Discovery Pharmaceutical Applications - Antidepressants (Tricyclic) from Serum App Note 63 1 T499127
Discovery Pharmaceutical Applications - Antihypertensive/Antiarrhythmic Compounds from Serum App Note 67 1 T499127
Discovery Pharmaceutical Applications - Antiulcer Compounds from Serum App Note 62 1 T499127
Discovery Pharmaceutical Applications - Barbiturates from Serum App Note 64 1 T499127
Discovery Pharmaceutical Applications - Bronchodilator (Caffeine Metabolites) from Serum App Note 57 1 T499127
Discovery Pharmaceutical Applications - Nonsteroidal Antiinflammatory Drugs from Serum App Note 59 1 T499127
Simple Solid Phase Extraction and HPLC Analysis of Catecholamines in Plasma App Note 66 130 2 T395066
Natural Products  
Discovery Pharmaceutical Applications - Chlorophyll from Methanolic Plant Extracts App Note 64 1 T499127
Discovery Pharmaceutical Applications - Humic Acids from Water App Note 63 1 T499127
Discovery Pharmaceutical Applications - Phloroglucinol from Water App Note 62 1 T499127
Discovery Pharmaceutical Applications - Tannic Acid from Water or Methanol App Note 62 1 T499127

 

SPE Theory & Method Development

Systematic Method Development (Case Studies)
Guides and Performance Tips

Category / Title Type Size (kb) No. Pages I.D.
Systematic Method Development (Case Studies)  
Comparison of a systematically developed method using Discovery DSC-8 SPE 96-Well Plate Vs. a generic method using conventional C18 Tech Report 102 8 T403039
The Selective Extraction and HPLC Analysis of Corticosteroids from Urine Using Discovery DSC-CN SPE Tech Report 1,263 8 T403042
A Case Study in SPE Method Development- Understanding the Dual Interaction Properties of Discovery DSC-SCX SPE Using Verapamil (and Metabolite) from Serum (Online Reporter 21.10) Article n/a n/a n/a
Systematic SPE Method Development for Bioanalyses Presentation 1,166 47 T404060
An Efficient Approach for Solid Phase Extraction for Reducing Ion Suppression in Liquid Chromatography /Mass Spectrometry (LC/MS) Presentation 365 16 T403108
Guides and Performance Tips  
Guide to Solid Phase Extraction Bulletin 910 319 12 T197910
Achieve Cleaner Extracts on More Selective Phase Chemistries (Reporter Vol 2, Issue 3) Article 109 3 T203015
Performance Tip - Conditioning & Equilibration on 96-Well Plates (Reporter 18.2) Article 107 1 T200012
Performance Tip - Proper pH Selection will Improve your SPE Extractions (Reporter 19.1) Article 129 1 T201001
Increase Productivity by Minimizing Processing Time Between Solid Phase Extraction (SPE) and High Performance Liquid Chromatography (HPLC) Analysis (Reporter 19.4) Article 936 4 T201004
LC-MS Ionization Effect from Solid Phase Extraction Extractables (Reporter 24.4) Article 258 3 T206004
Performance Tip - The Role of Flow Rate in Solid Phase Extraction (Reporter 19.7) Article 156 1 T201007
Controlling SPE Selectivity through pH and Organic Modifier Manipulation (Reporter 24.1) Article 827 2 T206001
Sample Pretreatment prior to SPE may Improve Extraction Performance (Reporter Vol 2, Issue 3) Article 45 1 T203015
The Utility of Reversed-Phase SPE Sorbents other than C18 (Reporter Vol 2, Issue 4) Article 31 1 T203016
Improve Sample Prep Selectivity through 96-well SPE Method Development Plates (Reporter 24.5) Article 308 3 T206005
Systematic Evaluation of SPE Chemistries for the Determination of Acidic, Neutral, and Basic Drugs Presentation 217 25 T404049
Overview of SPE Technology/Method Development & New Trends in Sample Preparation
Presentation 2,449 132 T407048

 

Product Information

Discovery®
SupelMIP™
Adsorbents
Dispersive SPE
3M Empore™
HybridSPE®
Supelclean™
SPE Accessories
 

Category / Title Type Size (kb) No. Pages I.D.
Discovery  
Discovery Reversed-Phase SPE Products Product Info. 81 2 T402053
Discovery DSC-MCAX (Mixed-Mode Cation Exchange) SPE Products Product Info. 510 2 T403137
Discovery Ion-Exchange SPE Products Product Info. 76 2 T402054
Discovery Normal Phase SPE Products Product Info. 73 2 T402052
96-Well SPE Method Development Plate, BAN, 25 mg/well Data Sheet 39 2 T706004
Discovery Ag-ION SPE Data Sheet 86 2 T706002
Case Study: Resolving CombiChem Purification Problems (Reporter 19.1) Article 127 1 T201001
High Throughput Sample Preparation of Acidic, Basic, and Neutral Drugs in Serum Using 96-Well SPE Plates Presentation 628 14 T401045
Discovery SPE-96 Well Plates - Applications App Note 165 44 2 T300165
SupelMIP  
SupelMIP SPE Brochure Brochure 981 12 T407075
SupelMIP SPE Product Flyer Product Info. 373 2  
Selective extraction using molecularly imprinted polymers Chart 297 1 T407060
Extraction of Nitroimidazoles from Milk and Egg Samples using SupelMIP SPE Nitroimidazoles and LC-MS-MS Tech Report 408 3 T409097
SupelMIP SPE – Amphetamines Instruction Sheet Data Sheet 78 2 T707011
SupelMIP SPE – Beta-agonists Instruction Sheet Data Sheet 112 3 T706020
SupelMIP SPE – Beta-blockers Instruction Sheet Data Sheet 96 3 T706025
SupelMIP SPE – Clenbuterol Instruction Sheet Data Sheet 70 2 T706019
SupelMIP SPE – Chloramphenicol Instruction Sheet Data Sheet 70 2 T706024
SupelMIP SPE – Full beta-receptors (beta-agonists and beta-blockers) Instruction Sheet Data Sheet 132 2 T706030
SupelMIP SPE – Nitroimidazoles Instruction Sheet Data Sheet 68 2 T709075
SupelMIP SPE – NNAL Instruction Sheet Data Sheet 116 2 T706021
SupelMIP SPE – Riboflavin (Vitamin B2) Instruction Sheet Data Sheet 82 2 T706022
SupelMIP SPE – Triazines Instruction Sheet Data Sheet 70 2 T706023
SupelMIP SPE – TSNAs Instruction Sheet Data Sheet 128 2 T706031
The Class-Selective Extraction and Analysis of β-Receptor Agonist and Antagonists using Molecularly Imprinted Polymer SPE (TheReporter 25.4) Article 218 3 T207004
Adsorbents  
Pre-Activated Florisil, Ampulized Data Sheet for Dioxin Prep - Florisil Version Data Sheet 39 1 T706014
LRA - Lipid Removal Agent Data/Instruction Sheet Data Sheet 41 2 T706006
Celite Analytical Filter Aid (CAFA II) (Analytix, Issue 4 - 2005) Article 48 1 n/a
Carbon Adsorbent Kits from Supelco (Analytix, Issue 2 - 2006) Article 201 2 T406050
Carbon Adsorbents for Air Sampling, GC and other analytical uses. Composition and role of physical parameters (European Reporter, Vol. 22) Article 59 1 n/a
Carbon Adsorbent Kits for Sample Prep and Method Development (Reporter 23.1) Article 129 2 T205001
Characterization of Polymer Carbon Sieves, Graphitized Polymer Carbons and Graphitized Carbon Blacks for Sample Preparation Applications Presentation 858 20 T410103H
Graphitized Carbon Blacks for Use in Sample Preparation Applications Presentation 465 23 T407012
Characterization of Carbon SPE for the Extraction of Polar Analytes Presentation 372 17 T497277
Dispersive SPE  
QuEChERS Multiresidue Method Flyer 218 2 JWP
Dispersive SPE (dSPE) Product Line Data Sheet 37 2 T706013
Extraction and Analyses of Agricultural Pesticides from Oranges Using the "QuEChERS" Method (TheReporter 24.3) Article 381 3 T206003
NEW Custom “Dispersive” SPE Products for Pesticide and Acrylamide Analysis (TheReporter 23.4) Article 383 2 T205004
The Extraction & Analysis of Multi-Residue Pesticides in Oranges Using Dispersive SPE & GC-MS Presentation 196 20 T406100
3M Empore  
General
Empore® Solid Phase Extraction (SPE) Products Product Info. 275 2 T409127
Improving Throughput with Empore SPE Tech Report 27 4 T409144
An Evaluation of Particle Fines in Empore SPE 96-well Plates Tech Report 695 8 T409145
Empore Application Bibliography Bibliography 730 82 T409146
96-Well Plates
Empore 96-well SPE Brochure 615 8 T409147
Empore Universal Resin 96-well  Product Info. 75 2 T409148
Empore High Throughput Pharmaceutical Bioanalysis Tech Report 154 8 T409149
Empore 96-well Guide to Method Optimization Tech Report 81 8 T409150
Empore 96-well Filter Plate - Instructions Instructions 79 8 T709086
Empore Universal Resin 96-well - Instructions Instructions 104 12 T709087
Empore MPC (Mixed-Phase Cation) 96-well - Instructions Instructions 110 12 T709088
Empore MPC C18 96-well - Instructions Instructions 105 12 T709089
Cartridges
Empore SPE Cartridges Brochure 248 8 T409151
Empore SPE Cartridges - FAQ Product Info. 194 12 T409152
Empore SPE Cartridges Instructions 162 12 T709090
Amiodarone in Serum using C18 Empore SPE Cartridges App Note 66 6 T309188
Extraction Disks
Empore SPE Disks Brochure 186 8 T409153
Empore Carbon Disk - Flyer Product Info. 16 1 T409156
Empore Oil & Grease Disks Product Info. 92 2 T409154
Empore Oil & Grease Disks - FAQ Product Info. 20 3 T409155
Empore C18 - Tips for Improving Recovery for EPA 525.1 Product Info. 66 1 T409157
Empore Oil & Grease Disk - Horizon SPE-DEX 4790 Extractor/Controller Instructions 18 3 T709091
Empore Anion-SR Disk Instructions Instructions 1.4mb 8 T709092
Empore SDB-XC Instructions Instructions 1.2mb 8 T709093
Empore SDB-RPS Instructions Instructions 1.3mb 8 T709094
Empore Oil & Grease Disk Instructions Instructions 1.4mb 8 T709095
Empore Cation-SR Disk Instructions Instructions 1.4mb 8 T709096
Empore C18 & C8 Disk Instructions Instructions 1.3mb 8 T709097
Empore Carbon Disk - Instructions Instructions 1.2mb 8 T709098
Empore Chelation Disk - Instructions Instructions 19 4 T709099
Empore C18 Disk EPA 506 Method Summary Instructions 18 2 T709100
Empore C18 Disk EPA 507 Method Summary Instructions 19 2 T709101
Empore C18 Disk EPA 508.1 Method Summary Instructions 19 2 T709102
Empore SDB (RPS) EPA 515.2 Method Summary Instructions 18 2 T709103
Empore C18 EPA 525.2 Method Summary Instructions 21 2 T709104
Empore C8 EPA 549.1 Method Summary Instructions 18 2 T709105
Empore C18 EPA 550.1 Method Summary Instructions 18 2 T709106
Empore Anion EPA 552.1 Method Summary Instructions 32 2 T709107
Empore SDB (RPS) or C18 EPA 553 Method Summary Instructions 17 2 T709108
Empore C18 EPA 1613 (Rev. B) Method Summary Instructions 18 2 T709109
Empore Oil & Grease EPA 1664 Method Summary Instructions 30 2 T309189
Empore SDB-XC SW 846 Method 3535 Summary Instructions 24 6 T709110
Empore C18 EPA QTM: PAHs Method Summary Instructions 19 2 T709111
Empore C18 EPA QTM: Pesticides & PCBs Method Summary Instructions 18 2 T709112
Empore C18 EPA QTM: Phenols Method Summary Instructions 17 2 T709113
Lead from Maple Syrup using Empore Chelation Disk App Note 16 2 T309190
Imiquimod & Metabolites in Large Volumes of Urine using Empore Disks App Note 66 6 T309191
HybridSPE  
HybridSPE-Precipitation Technology Product Info. 483  T408102
Instructions/Data Sheet & Troubleshooting Guide for HybridSPE Data Sheet 76  T708008
Enrichment of Phospholipids in Biological Samples Using HybridSPE (Reporter 28.3) Article 176 T210003
Minimizing Phospholipid Matrix Effects in HILIC LC-MS using HybridSPE-Precipitation Small Volume Plates (Reporter 28.2) Article 338 T210002
Supelclean  
Supelclean ENVI-Carb Plus Data Sheet 100 1 T708003
Supelclean Sulfoxide Data Sheet 42 2 T707009
SPE Accessories  
Visiprep Large Volume Sampler Product Info. 161 2 T495023
Visiprep Solid Phase Extraction Vacuum Manifolds Product Info. 285 2 T495121
Instructions for VisDry Drying Attachment Data Sheet 13 2 W97875
Long Stem Valve for VisiDry Drying Attachment Data Sheet 13 1 W710050
Large Volume Sampler Data Sheet 72 1 W794031
Instructions for Assembling and Using Visiprep and Visiprep DL Solid Phase Extraction Vacuum Manifolds Data Sheet 305 4 T795041