Phase Selection

Standard SPE Phases
Specialty SPE Phases

Standard SPE Phases

Your Sample Matrix is:	Aqueous (biological fluids, water, aqueous extracts of tissues, etc.)				Organic (organic extracts of tissues, hexane, dichloromethane, etc.)
	________\|_________________ ________________\|_______ \|_________________________\| \|_______________________\|
Recommended Retention Mechanism:	Reversed-Phase		Ion-Exchange				Normal Phase
Analyte Characteristics:	Moderately polar to non-polar compounds		Weak cations / anions		Strong cations / anions		Polar to moderately polar compounds
Application	Pharma.	Environ.	Pharma.	Environ.	Pharma.	Environ.	Pharma.	Environ.
Recommended SPE Phase:	DSC-18 DSC-18Lt DSC-8 DSC-Ph DSC-CN DPA-6S	ENVI™-18 ENVI-8 ENVI-Chrom P LC-18 LC-8 LC-Ph LC-CN	DSC-SAX DSC-SCX	LC-SAX LC-SCX	DSC-WCX DSC-NH₂	LC-WCX LC-NH₂ PSA	DSC-Si DSC-CN DSC-Diol DSC-NH₂	ENVI-Florisil® LC-Alumina LC-Florisil LC-Si LC-NH₂ LC-Diol LC-CN PSA

The SPE Tube Configuraton Guide will help you choose the appropriate bed weight and cartridge dimensions.

NEW! Supelco now offers SPE sample MultiPaks to make the phase selection process easier.

Specialty SPE Phases

Phase Description	Application
SupelMIP™ SPE Tubes	Molecular imprinted polymers for the highly selective extraction of trace analytes in difficult sample matrices
Supel-Select HLB SPE	Hydrophilic modified styrene polymer ideal for extracting a very broad range of compounds from aqueous samples… at a price you desire!
Supelclean™ Sulfoxide SPE	Trace level extraction of PCBs and other aromatic compounds from difficult oil samples under normal-phase conditions
Supelclean Coconut Charcoal SPE	Extraction of nitrosamines in drinking water (US EPA Method 521)
Supelclean ENVI-Carb Plus SPE	Spherical carbon particles engineered for the extraction of highly polar compounds from aqueous samples such as drinking and ground water.
Discovery DSC-MCAX	Mixed-mode cation exchange for superior selectivity/sample cleanup when extracting basic compounds (most pharmaceuticals) from biological fluids (e.g., plasma, urine, etc.)
Discovery Ag-Ion	Silver Ion SPE for the fractionation of cis-trans isomers and other FAMEs
Polymer SAX Rezorian™ Cartridge	Strong cation and anion exchanger on a styrene base particle. Offers much higher ion-exchange capacity Polymer SCX Reversible Tube than silica based ion-exchangers
Discovery DPA-6S	Polyamide resin that adsorbs polar compounds containing multi –OH and –COOH groups. Useful for extracting polyphenolics and other natural compounds (e.g., flavenoids, chlorophyll, humic acid, etc.) from plant extracts
Supelclean™ ENVI-18 and –8 DSK SPE Disks	Provides fast flow rates for processing large volumes of water samples (≥ 0.5 L). Used in EPA 500 series methods – Drinking Water
Supelclean ENVI-Carb	Extreme affinity for polar compounds in aqueous samples and water miscible organic extracts. Commonly used in pesticide analysis of food samples
Multi-layer Supelclean SPE Products (ENVI-Carb™, SAX, PSA, NH₂)	Developed to provide superior cleanup when conducting multi-residue pesticide analysis in food/agricultural matrices
Supelclean LC-4 (wide pore)	Used for desalting proteins/peptides and other macromolecules
Dual Layer Florisil/Na₂SO₄	For total petroleum hydrocarbon index according to European Method EN9377-2

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