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Solid Phase Extraction
Supel™-Select HLB SPE
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Sample Prep Performance at the Price you Desire!
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Supelco’s Supel-Select HLB SPE is a hydrophilic modified styrene based polymer developed for the solid phase extraction of a broad range of compounds from aqueous samples. The retention mechanism is predominately based on reversed-phase interaction. However, because the phase is hydrophilic modified, the phase is also selective for more polar compounds. Examples of more polar compounds that are retained and recovered on Supel-Select HLB include (but are not limited to): pyridoxine (logPo/w -0.56), riboflavin (logPo/w -2.02), biotin (logPo/w 0.11).
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| Phase chemistry: |
Hydrophilic modified styrene polymer |
| pH Compatibility: |
0-14 |
| Particle Size: |
55-60 µm |
| MS friendly: |
Yes |
| Surface area: |
400-410 m2/g |
| Pore volume: |
0.88 mL/g |
| Pore size: |
87 Å |
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Request a FREE Supel-Select HLB SPE Sample Pack.
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| Feature |
Benefit |
| Hydrophilic modified styrene resin |
Extract and recover a broad range of analytes (polar to non-polar, acidic to basic) using a single sorbent |
| Generic methodology |
Save time, money, and headache during method development |
| Greater capacity |
Allows for smaller bed weights = smaller elution volumes = time savings in sample processing |
| Resistant to overdrying |
More robust methodology |
| Low UV and MS extractables |
Lower background for greater sensitivity |
| Stringent production & QC |
Greater lot-to-lot, tube-to-tube, and well-to-well consistency for improved accuracy and precision |
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Minimal Extractables
Supel-Select HLB SPE phases are quality controlled for both LC-UV and LC-MS/MS extractables. As assays require greater sensitivity, analytical “cleanliness” of both SPE phases and associated hardware becomes more critical. In this simple test, acetonitrile was passed through both Supel-Select HLB SPE tubes and the leading competitor’s tubes followed by LC-UV analysis.
Supel-Select HLB SPE imparted less than 25% of UV extractables than the leading competitor.
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| Ordering Information |
| Description |
Qty/Pk |
Cat. No. |
| Supel-Select HLB SPE |
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30 mg/1 mL |
100 |
54181-U |
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60 mg/3 mL |
50 |
54182-U |
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200 mg/6 mL |
30 |
54183-U |
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500 mg/12 mL |
20 |
54184-U |
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1 g/20 mL |
20 |
54186-U |
| Supel-Select HLB 96-well SPE |
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10 mg/ well |
1 |
Inquire |
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30 mg /well |
1 |
575661-U |
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60 mg/ well |
1 |
575662-U |
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