Attention: Website ordering limitations

Sigma-Aldrich is currently experiencing a problem with our order management system. This impacts Africa, Europe, South America and most of Asia. During this time web ordering and real-time pricing and product availability are unavailable. Please contact your local Sigma-Aldrich office for assistance.

Sample Preparation & Purification

Solid Phase Microextraction (SPME)

SPME FFA for Automated Fiber Exchange
SPME Products and Accessories (Ordering Information)
Fiber Selection Guide
Performance Tips for Sampling Volatiles & Semivolatiles
Sample Matrix Considerations
Frequently Asked Questions
SPME Applications
SPME Literature
Custom SPME Fiber Request

Solid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating removes the compounds from your sample by absorption in the case of liquid coatings or adsorbtion in the case of solid coatings.   The SPME fiber is then inserted directly into the chromatograph for desorption and analysis. SPME has gained wide spread acceptance as the technique of preference for many applications including flavors and fragrances, forensics and toxicology, environmental and biological matrices, and product testing to name a few.

We have developed an Applications Guide listing applications that have been published on the use of SPME. 

If you have any questions or a sample preparation problem, contact us by e-mail at techservice@sial.com or call our technical service department at 814-359-3041 (US & Canada 800-359-3041).