Sample Preparation & Purification

Solid Phase Microextraction (SPME)

Solid Phase Microextraction (SPME) is an innovative, solvent-free sample prep technology that is fast, economical, and versatile. SPME uses a fiber coated with a liquid (polymer), a solid (sorbent), or a combination of both. The fiber coating extracts the compounds from your sample by absorption in the case of liquid coatings or absorption in the case of solid coatings.   The SPME fiber is then inserted directly into the chromatograph for desorption and analysis. SPME has gained widespread acceptance as the technique of preference for many applications including flavors and fragrances, forensics and toxicology, environmental and biological matrices, and product testing to name a few. We have developed an Application Reference Guide listing over 3000 applications that have been published on the use of SPME.  




Fiber Selection Guide
Determine the type of fiber you need
according to the analyte, its molecular
weight and polarity.


Performance Tips
SPME fibers and their capacity for collection of volatile and semi-volatile compounds.


SPME Videos
View our SPME video selection to learn how the SPME technique can meet your sample preparation needs.