NAV3 - neuron navigator 3
Entrez Gene Name: neuron navigator 3
Entrez GeneID: Human(89795)
, Mouse(260315), Rat(314814)
, Mouse(260315), Rat(314814) Synonyms: 4732483H20RIK, 9630020C08, 9630020C08Rik, KIAA0938, mKIAA0938, NAV3, POMFIL1, Pomfil1p, RGD1306259, STEERIN3, unc53H3
Gene Summary
- Human (89795): This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined.
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
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Literature References
- 16166283Karenko L, Hahtola S, Päivinen S, Karhu R, Syrjä S, Kähkönen M, Nedoszytko B, Kytölä S, Zhou Y, Blazevic V, Pesonen M, Nevala H, Nupponen N, Sihto H, Krebs I, Poustka A, Roszkiewicz J, Saksela K, Peterson P, Visakorpi T, Ranki A. Primary Cutaneous T-Cell Lymphomas Show a Deletion or Translocation Affecting NAV3, the Human UNC-53 Homologue.Cancer Res 2005 Sep 15;65(18):8101-10
- 17617570Okuda M, Togawa A, Wada H, Nishikawa S. Distinct Activities of Stromal Cells Involved in the Organogenesis of Lymph Nodes and Peyer's Patches.J Immunol 2007 Jul 15;179(2):804-11
- 16104056Omenn GS, States DJ, Adamski M, Blackwell TW, Menon R, Hermjakob H, Apweiler R, Haab BB, Simpson RJ, Eddes JS, Kapp EA, Moritz RL, Chan DW, Rai AJ, Admon A, Aebersold R, Eng J, Hancock WS, Hefta SA, Meyer H, Paik YK, Yoo JS, Ping P, Pounds J, Adkins J, Qian X, Wang R, Wasinger V, Wu CY, Zhao X, Zeng R, Archakov A, Tsugita A, Beer I, Pandey A, Pisano M, Andrews P, Tammen H, Speicher DW, Hanash SM. Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database.Proteomics 2005 08 1;5(13):3226-45 View 15 categorized literature findings and their references in IPA
