BAZ1B - bromodomain adjacent to zinc finger domain, 1B
Entrez Gene Name: bromodomain adjacent to zinc finger domain, 1B
Entrez GeneID: Human(9031)
, Mouse(22385), Rat(368002)
, Mouse(22385), Rat(368002) Synonyms: BAZ1B, C87820, WBSCR10, WBSCR9, WSTF
Gene Summary
- Human (9031): This gene encodes a member of the bromodomain protein family. The bromodomain is a structural motif characteristic of proteins involved in chromatin-dependent regulation of transcription. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
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Biological Process
chromatin assembly or disassembly, chromatin remodeling, regulation of transcription, DNA-dependent, transcription
Literature References
- 11980720Bozhenok L, Wade PA, Varga-Weisz P. WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.EMBO J 2002 May 1;21(9):2231-41
- 12837248Kitagawa H, Fujiki R, Yoshimura K, Mezaki Y, Uematsu Y, Matsui D, Ogawa S, Unno K, Okubo M, Tokita A, Nakagawa T, Ito T, Ishimi Y, Nagasawa H, Matsumoto T, Yanagisawa J, Kato S. The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome.Cell 2003 06 27;113(7):905-17
- 15543136Poot RA, Bozhenok L, van den Berg DL, Steffensen S, Ferreira F, Grimaldi M, Gilbert N, Ferreira J, Varga-Weisz PD. The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci.Nat Cell Biol 2004 Dec 01;6(12):1236-44 View 68 categorized literature findings and their references in IPA
Molecular Functions
metal ion binding, protein binding, transcription factor activity, zinc ion binding
