ASAP1 - ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Entrez Gene Name: ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
Entrez GeneID: Human(50807)
, Mouse(13196), Rat(314961)
, Mouse(13196), Rat(314961) Synonyms: AMAP1, ASAP1, AV239055, CENTB4, DDEF1, KIAA1249, mKIAA1249, PAG2, PAP, s19, ZG14P
Gene Summary
No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Literature References
- 17893324Bharti S, Inoue H, Bharti K, Hirsch DS, Nie Z, Yoon HY, Artym V, Yamada KM, Mueller SC, Barr VA, Randazzo PA. Src-Dependent Phosphorylation of ASAP1 Regulates Podosomes.Mol Cell Biol 2007 Dec 01;27(23):8271-83
- 16636290Hashimoto S, Hirose M, Hashimoto A, Morishige M, Yamada A, Hosaka H, Akagi K, Ogawa E, Oneyama C, Agatsuma T, Okada M, Kobayashi H, Wada H, Nakano H, Ikegami T, Nakagawa A, Sabe H. Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.Proc Natl Acad Sci U S A 2006 May 02;103(18):7036-41
- 17255943Nam JM, Onodera Y, Mazaki Y, Miyoshi H, Hashimoto S, Sabe H. CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.EMBO J 2007 02 7;26(3):647-56 View 271 categorized literature findings and their references in IPA
Molecular Functions
ARF GTPase activator activity, GTPase activator activity, metal ion binding, protein binding, zinc ion binding
Protein Domains
ankyrin repeat, C4 type zinc finger domain, pleckstrin homology (PH) domain, protein binding, SH3 domain, Src binding domain
