FBXO44 - F-box protein 44
Entrez Gene Name: F-box protein 44
Entrez GeneID: Human(93611)
, Mouse(230903), Rat(500587)
, Mouse(230903), Rat(500587) Synonyms: 5730411K09, AV001623, DKFZp781J0852, F-box protein FBX30, FBG3, FBX30, Fbx44, FBX6A, FBXO44, FBXO6A, MGC14140, RGD1562463
Gene Summary
- Human (93611): This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
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Literature References
- 15502875John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets.PLoS Biol 2004 11 1;2(11):e363 View 2 categorized literature findings and their references in IPA
