SLC6A12 - solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Entrez Gene Name: solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
Entrez GeneID: Human(6539)
, Mouse(14411), Rat(50676)
, Mouse(14411), Rat(50676) Synonyms: BETAINE TRANSPORTER, BGT-1, FLJ38727, Gabt2, Gat1, GAT2, RNU28927, SLC6A12, VGAT
Gene Summary
- Rat (50676): sodium/chloride-dependent neurotransmitter transport protein; expressed in exocytotic vesicles in GABAergic cells; associated with exocysts [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Role in cell:
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Literature References
- 17761765Manzano J, Cuadrado M, Morte B, Bernal J. Influence of Thyroid Hormone and Thyroid Hormone Receptors in the Generation of Cerebellar {gamma}-Aminobutyric Acid-Ergic Interneurons from Precursor Cells.Endocrinology 2007 Dec 01;148(12):5746-51
- 16772300Tsai TT, Danielson KG, Guttapalli A, Oguz E, Albert TJ, Shapiro IM, Risbud MV. TonEBP/OREBP Is a Regulator of Nucleus Pulposus Cell Function and Survival in the Intervertebral Disc.J Biol Chem 2006 Sep 01;281(35):25416-24
- 10228153Perego C, Vanoni C, Villa A, Longhi R, Kaech SM, Frohli E, Hajnal A, Kim SK, Pietrini G. PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells.EMBO J 1999 May 4;18(9):2384-93 View 49 categorized literature findings and their references in IPA
Molecular Functions
gamma-aminobutyric acid:sodium symporter activity, neurotransmitter:sodium symporter activity, symporter activity
