KAZALD1 - Kazal-type serine peptidase inhibitor domain 1
Entrez Gene Name: Kazal-type serine peptidase inhibitor domain 1
Entrez GeneID: Human(81621)
, Mouse(107250), Rat(293997)
, Mouse(107250), Rat(293997) Synonyms: AI842353, BONO1, FKSG28, FKSG40, FLJ24094, IGFBP-rP10, KAZALD1, MGC125157
Gene Summary
- Human (81621): This gene encodes a secreted member of the insulin growth factor-binding protein (IGFBP) superfamily. It contains an N-terminal insulin growth factor-binding domain, a central Kazal-type serine protease inhibitor and follistatin-like domain, and a C-terminal immunoglobulin-like domain. Studies of the mouse ortholog suggest that this gene product may have a function in bone development and bone regeneration. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
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Biological Process
cell differentiation, extracellular matrix organization, multicellular organismal development, ossification, regulation of cell growth
Cellular Components
extracellular matrix, extracellular region, extracellular space, interstitial matrix, proteinaceous extracellular matrix
Literature References
- 18757743Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K. Transcriptome-based systematic identification of extracellular matrix proteins.Proc Natl Acad Sci U S A 2008 09 2;105(35):12849-54 View 1 categorized literature findings and their references in IPA
