KANK1 - KN motif and ankyrin repeat domains 1
Entrez Gene Name: KN motif and ankyrin repeat domains 1
Entrez GeneID: Human(23189)
, Mouse(107351)
, Rat(309429)
Synonyms: A930031B09RIK, ANKRD15, ANKYRIN REPEAT DOMAIN PROTEIN 15, AU015049, AW121052, D330024H06Rik, DKFZp451G231, KANK, KANK1, KIAA0172, MGC125169, MGC43128, MGC90826, mKIAA0172
Gene Summary
- Human (23189): This gene encodes a protein containing four ankyrin repeat domains in its C-terminus. The suggested role for this protein is in tumorigenesis of renal cell carcinoma. Two alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Regulates:
| Role in cell:
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Biological Process
negative regulation of actin filament polymerization, negative regulation of cell cycle
Literature References
- 15685193
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J, Bartel DP, Linsley PS, Johnson JM. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs.Nature 2005 02 17;433(7027):769-73 - 15502875
John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets.PLoS Biol 2004 11 1;2(11):e363 - 18292579
Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL. Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and Positive and Negative Cross-Talk with Bacterial Lipopolysaccharide.J Immunol 2008 Mar 01;180(5):3520-34 View 14 categorized literature findings and their references in IPA



