GRIN2D - glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Entrez Gene Name: glutamate receptor, ionotropic, N-methyl D-aspartate 2D
Entrez GeneID: Human(2906)
, Mouse(14814), Rat(24412)
, Mouse(14814), Rat(24412) Synonyms: EB11, GRIN2D, NMDAR2D, NR2D
Gene Summary
- Rat (24412): N-methyl-D-aspartate receptor subunit; expressed in mid-brain structures with peak expression at day P7 [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Biological Process
adult locomotory behavior, detection of mechanical stimulus involved in sensory perception of pain, ion transport, regulation of excitatory postsynaptic membrane potential, regulation of sensory perception of pain, signal transduction, startle response, synaptic transmission, glutamatergic, transport
Cellular Components
cell junction, integral to membrane, ionotropic glutamate receptor complex, membrane, N-methyl-D-aspartate selective glutamate receptor complex, plasma membrane, postsynaptic membrane, synapse, synaptosome
Literature References
- 17329232Carter CJ. EIF2B and Oligodendrocyte Survival: Where Nature and Nurture Meet in Bipolar Disorder and Schizophrenia?Schizophr Bull 2007 Nov 01;33(6):1343-53
- 17188796Fan MM, Raymond LA. N-methyl-D-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease.Prog Neurobiol 2007 Apr 01;81(5-6):272-93
- 11144360Ehlers MD. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting.Neuron 2000 Nov 1;28(2):511-25 View 715 categorized literature findings and their references in IPA
Molecular Functions
calcium ion binding, cation channel activity, extracellular-glutamate-gated ion channel activity, glutamate binding, ion channel activity, ionotropic glutamate receptor activity, magnesium ion binding, N-methyl-D-aspartate selective glutamate receptor activity, neurotransmitter binding, protein binding, receptor activity, voltage-gated cation channel activity
Protein Domains
carboxy terminal domain, cation channel, extracellular ligand binding domain, glutamate binding, ion channel, ionotropic glutamate receptor, N-methyl-D-aspartate selective glutamate receptor, neurotransmitter binding, protein binding
