POLI - polymerase (DNA directed) iota
Entrez Gene Name: polymerase (DNA directed) iota
Entrez GeneID: Human(11201)
, Mouse(26447), Rat(291526)
, Mouse(26447), Rat(291526) Synonyms: DNA POLYMERASE IOTA, POLI, RAD30B, RAD3OB
Gene Summary
No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Regulates:
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Literature References
- 16189514Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M. Towards a proteome-scale map of the human protein-protein interaction network.Nature 2005 Oct 20;437(7062):1173-8
- 12606586Kannouche P, Fernandez De Henestrosa AR, Coull B, Vidal AE, Gray C, Zicha D, Woodgate R, Lehmann AR. Localization of DNA polymerases eta and iota to the replication machinery is tightly co-ordinated in human cells.EMBO J 2003 Mar 3;22(5):1223-1233
- 17409408Wang Y, Woodgate R, McManus TP, Mead S, McCormick JJ, Maher VM. Evidence that in Xeroderma Pigmentosum Variant Cells, which Lack DNA Polymerase {eta}, DNA Polymerase {iota} Causes the Very High Frequency and Unique Spectrum of UV-Induced Mutations.Cancer Res 2007 Apr 01;67(7):3018-26 View 67 categorized literature findings and their references in IPA
Molecular Functions
damaged DNA binding, DNA binding, DNA-directed DNA polymerase activity, magnesium ion binding, metal ion binding, nucleotidyltransferase activity, transferase activity, transporter activity
