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EAF2 - ELL associated factor 2
Entrez Gene Name: ELL associated factor 2
Synonyms: AW048865, BM040, EAF2, Festa, FESTA-L, FESTA-S, TRAITS, U19

Gene Summary

No Data Available

Cell Regulation

Regulates:
  • ELL
View all 2 in IPA
Regulated by:
  • No Data Available
Binds:
  • TFPT
  • ELL
View all 4 in IPA
Role in cell:
  • No Data Available
Disease:
  • non-insulin-dependent diabetes mellitus
View all 1 in IPA

Biological Process

apoptosis, induction of apoptosis, induction of apoptosis by intracellular signals, positive regulation of transcription, regulation of transcription, DNA-dependent, transcription

Cellular Components

nuclear speck, nucleoplasm, nucleus

Literature References

  • 17554300Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.Nature 2007 06 7;447(7145):661-78
  • 12761297Saso K, Ito T, Natori S, Sekimizu K. Identification of a novel tissue-specific transcriptional activator FESTA as a protein that interacts with the transcription elongation factor S-II.J Biochem (Tokyo) 2003 04 1;133(4):493-500
  • 17395368Jiang F, Ai J, Xiao W, Wang Z. FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity.Cancer Lett 2007 08 18;253(2):265-72
  • View 11 categorized literature findings and their references in IPA

Molecular Functions

protein binding, transcription activator activity

Pathways

No Data Available

Protein Domains

protein binding, transcription regulator, transcriptional activator

Subcellular Locations

nuclear speckles, nucleus

IPA Extras

View additional information available in IPA's curated and annotated database: