EAF1 - ELL associated factor 1
Entrez Gene Name: ELL associated factor 1
Entrez GeneID: Human(85403)
, Mouse(74427), Rat(306261)
, Mouse(74427), Rat(306261) Synonyms: 4933403C17Rik, AI666536, EAF1
Gene Summary
No Data Available
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Role in cell:
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Biological Process
positive regulation of transcription from RNA polymerase II promoter, regulation of transcription, DNA-dependent, transcription
Literature References
- 12686606Polak PE, Simone F, Kaberlein JJ, Luo RT, Thirman MJ. ELL and EAF1 are Cajal Body Components That Are Disrupted in MLL-ELL Leukemia.Mol Biol Cell 2003 Apr;14(4):1517-28
- 11418481Simone F, Polak PE, Kaberlein JJ, Luo RT, Levitan DA, Thirman MJ. EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.Blood 2001 Jul 1;98(1):201-9
- 17554300Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.Nature 2007 06 7;447(7145):661-78 View 70 categorized literature findings and their references in IPA
Protein Domains
protein binding, transcription factor binding, transcription regulator, transcriptional activator
Subcellular Locations
cajal bodies, cytoplasm, nuclear fraction, nuclear speckles, nucleoplasm, nucleus
