CHRNA10 - cholinergic receptor, nicotinic, alpha 10
Entrez Gene Name: cholinergic receptor, nicotinic, alpha 10
Entrez GeneID: Human(57053)
, Mouse(504186), Rat(64574)
, Mouse(504186), Rat(64574) Synonyms: Alpha10 nachr, CHRNA10, Nachr alpha 10
Gene Summary
- Rat (64574): alpha10 subunit of the nicotininc acetylcholine receptor (nAChR); may heterodimerize with alpha9 subunit [RGD]
Molecular Functions | Biological Process | Cellular Components | Protein Domains | Subcellular Locations | Pathways | Literature References | IPA Extras
Cell Regulation
Disease:
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Biological Process
calcium ion transport, cation transport, detection of mechanical stimulus involved in sensory perception of sound, inner ear morphogenesis, ion transport, regulation of cell proliferation, synaptic transmission, cholinergic, transport
Cellular Components
cell junction, integral to membrane, membrane, nicotinic acetylcholine-gated receptor-channel complex, plasma membrane, postsynaptic membrane, synapse
Literature References
- 9442882Thomas SM, Brugge JS. Cellular functions regulated by Src family kinases.Annu Rev Cell Dev Biol 1997;13:513-609
- 16375977Wrona D. Neural-immune interactions: an integrative view of the bidirectional relationship between the brain and immune systems.J Neuroimmunol 2006 Mar 01;172(1-2):38-58
- 15308777Sela M, Mozes E. Therapeutic vaccines in autoimmunity.Proc Natl Acad Sci U S A 2004 Oct 05;101 Suppl 2:14586-92 View 209 categorized literature findings and their references in IPA
Molecular Functions
calcium channel activity, calcium ion binding, extracellular ligand-gated ion channel activity, ion channel activity, neurotransmitter receptor activity, nicotinic acetylcholine-activated cation-selective channel activity, receptor activity, receptor binding
Protein Domains
extracellular ligand binding domain, neurotransmitter-gated ion channel ligand binding domain, nicotinic acetylcholine-activated cation-selective channel, receptor binding, transmembrane receptor
